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Danish researchers link the expression of three genes to being obese, but metabolically healthy, the Guardian reports.

In Nature this week: DNA methylation patters can uncover people at increased risk of diabetes, and more.

In PLOS this week: RNA-seq, ChIP-seq to determine metformin response; array-based approach to detect protozoa in blood; and more.

By studying variants in PCSK9, researchers reported the therapies targeting the gene would have some of the same effects as statins.

The company plans to recruit one million patients from Mexico over three years and then expand to Columbia, Argentina, and Brazil.

The single-cell approach enabled them to identify gene expression in rare cell types, highlighting a previously unrecognized role for these cells in diabetes. 

University of Cambridge researchers found that people who learned their genetic risk of developing diabetes did not have increased motivation to make lifestyle changes.

The effort aims to identify a suite of markers that could aid in management of type II diabetes and related conditions like retinopathy and kidney damage.

The companies will use Myriad RBM's CustomMAP platform to measure cardiovascular risk biomarkers in patients treated with a Sanofi diabetes drug.

The results of this meta-analysis by University of Cambridge-led team could have implications for LDL-C-lowering therapies.

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The General Data Protection Regulation has slowed some data sharing with non-European researchers as they find ways to comply with the law, ScienceInsider reports.

A bioethicist from Abertay University uses a utilitarian approach to justify genetically modifying the human germline, the BBC reports.

The US has upgraded its network of public health labs to provide whole-genome sequencing to track antibiotic-resistant bacteria, Quartz reports.

In Science this week: approach to visualize 3D genome structure in single cells, RNA interference knockdown screens to examine genetic origins of beetle horns and insect wings,  and more.