Using small RNA sequencing, investigators found miRNAs in the blood that track with cirrhosis, hepatitis, type 2 diabetes, or acetaminophen toxicity.
In Science this week: a protective gene in C. elegans, and combining EHRs with genetic data to ID HLA-associated variants
The researchers noted that 93 of the newly identified loci are found in both African-American and European populations, and only 18 are European-specific.
Using monogenic diabetes registry examples, a University of Chicago researcher argued that appropriate genetic testing is needed to detect monogenic diabetes.
At the American College of Medical Genetics and Genomics annual meeting in Phoenix, WuXi presented results from a pilot study involving 190 individuals.
The company, still collecting utility data, anticipates that this more complex analysis will lead to better personalization of health and wellness strategies for its clients.
In Science this week: genetic target for urothelial bladder cancer treatment, and more.
In PNAS this week: DNA regulation in islet cells, algorithm predicts regulatory element marks in various tissues, and more.
The study seeks to identify biomarkers that can help personalize treatment for patients by identifying signs of rapid decline in kidney function.
The collaborators plan to collect samples that will allow them insight into participants' microbiomes in order to understand disease mechanisms over time.
A UK woman is suing three National Health Service Trusts for not telling her about her father's Huntington's disease diagnosis, the BBC reports.
LiveScience reports that a novel mutation in the LPL gene was uncovered in three siblings with very high triglyceride levels.
The president of Nankai University is embroiled in a data manipulation scandal, the South China Morning Post reports.
In PNAS this week: cytotoxic CD4 T cell signature in supercentenarians, evolutionary history of beetles, and more.