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In Nature this week: a genomics search engine, and more.

The funding will support further development of an existing serum-based assay and expansion of the test to use saliva samples.

Two papers in Nature Genetics found that loss-of-function variants in ADCY3 were associated with severe obesity, and that ADCY3 could be a treatment target.

Diabetes Respite

University of Pittsburgh-led team finds that gene therapy could treat mice with type 1 diabetes for a few months, the Los Angeles Times reports.

Over the next three years, Immunovia and its partners will use the firm's Immray PanCan-d assay to screen 6,000 diabetes patients for pancreatic cancer.

The Salk Institute-led team developed a system for in vivo activation of endogenous target genes through trans-epigenetic remodeling.

A null mutation in the SERPINE1 gene was associated with longer telomeres and increased longevity among carriers, a new study found.

With exome and/or RNA sequences for dozens of insulinomas, researchers saw epigenetic, development, and other pathways prompting insulin-producing cell expansion.

The researchers believe that the discovery of the genetic loci linked to T2D and CHD will lead to therapeutic opportunities to lower the risk of both diseases.

Startups offering blockchain technology to support genomics and precision medicine still need to prove themselves and find markets.

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At the Lancet, more than two dozen public health researchers condemn the conspiracy theories that have emerged surrounding the source of the COVID-19 outbreak.

The Washington Post reports that Philip Leder, who helped uncover how DNA codes for proteins and studied the role of genes in cancer, has died.

Researchers from Trinity College Dublin and the University of Pittsburgh look into how often de novo genes arise and how important they may be.

In Nucleic Acids Research this week: pipeline for genotyping Alu retrotransposon mobile element insertions, previously undocumented non-coding RNAs, and more.