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diabetes

With the help of electronic health record data, researchers searched for common variants linked to hundreds of diseases or clinical lab measurements.

In Science this week: gut bacteria that influence effectiveness of a high-fiber diet in type 2 diabetes, and more.

Researchers found methylation mediators of obesity and other metabolic features by profiling individuals born after a famine called the Dutch Hunger Winter.

Family members with diabetes and others with insulinomatosis both harbor the same missense MAFA mutation.

In Nature this week: a genomics search engine, and more.

The funding will support further development of an existing serum-based assay and expansion of the test to use saliva samples.

Two papers in Nature Genetics found that loss-of-function variants in ADCY3 were associated with severe obesity, and that ADCY3 could be a treatment target.

Diabetes Respite

University of Pittsburgh-led team finds that gene therapy could treat mice with type 1 diabetes for a few months, the Los Angeles Times reports.

Over the next three years, Immunovia and its partners will use the firm's Immray PanCan-d assay to screen 6,000 diabetes patients for pancreatic cancer.

The Salk Institute-led team developed a system for in vivo activation of endogenous target genes through trans-epigenetic remodeling.

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A new paper says an effort to introduce gene drives into mosquitos altered the genetic makeup of the local mosquitos, but the company behind the project says the paper is flawed.

Virginia's Department of Forensic Science is offering attorneys a course on DNA testing, the Virginian-Pilot reports.

Researchers examine changes in the genomes of emmer wheat populations where the climate has warmed, the BBC reports.

In Cell this week: microinjection of CRISPR-Cas9 enables targeted mutations in Anolis, melanoma proteomic profiling, and more.