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Under the partnership the two companies will develop assays for insulin, proinsulin, and c-peptide on clinical sample cohorts at both Nuclea and IRCM's facilities.
The funding will be used to support four to five programs characterizing and validating genetic variations involved with the disease.
Researchers detected a truncating mutation in the carboxypeptidase E gene in members of a Sudanese family affected by extreme obesity, glucose metabolism problems, and other symptoms.
The partners will develop panels to stratify patients with obesity and diabetes into surgical and alternate intervention groups in an upcoming clinical trial.
The study, funded last month by the NIH, will use SRM-MS to identify proteins from a subset of promising pathways that are associated with DKD patients' progression to end-stage disease.
The partners are using genomic data to improve understanding of cardiovascular disease and diabetes and identify markers linked to drug response.
The Biomarker Development Center will use Singulex's Single Molecule Counting technology to quantify ultra-low level biomarkers.
The financing is an extension of a Series E round completed in early 2014 and brings the total amount in the round to $20 million.
Genetic study of familial hypercholesterolemia implicates link between type 2 diabetes risk and cholesterol transport.
Using the Immunochip, University of Virginia researchers fine-mapped type 1 diabetes susceptibility loci and examined potential causal variants.
A new analysis suggests warming, not the arrival of humans, led to the extinction of the woolly rhinoceros thousands of years ago, the Economist reports.
Chinese health officials uncovered SARS-CoV-2 viral RNA on imported frozen food, but the New York Times reports catching COVID-19 that way would be unlikely.
The UK has ordered 60 million coronavirus vaccine doses from Novavax and 30 million doses from Janssen, according to the Guardian.
In Science this week: machine learning model predicts whether ion channel mutations will cause disease, and more.