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The team said their approach may have several applications, including evaluation of cellular response to therapies, and early diagnosis of diseases like cancer.

Using mass spec analysis of pancreatic β cell extracts, they identified peptides that appeared responsible for T cell responses involved in the disease.

Michael Snyder

Snyder's new book, "Genomics and Personalized Medicine," serves as a primer for patients and doctors, touching on topics from tailored cancer therapy to wearable devices.

A type 2 diabetes genome-wide association meta-analysis involving tens of thousands of Japanese individuals uncovered risk loci relevant to other populations.

The researchers demonstrated that blocking the functioning of certain genes expanded the lifespan of lab animals.

In Genome Biology this week: genome and transcriptome of the cinereous vulture, subtractive assembly strategy for comparing microbial communities, and more.

In Science this week: immunogenic mutations in GI cancers, and more.

The study highlights the utility of using genetic and phenotypic data from large populations to enable better diagnosis and tailored treatment. 

Using genotyping data, the Children's Hospital of Philadelphia-led team found high heritability across pediatric-onset autoimmune diseases.

Researchers will study how prior hypoglycemic episodes can result in the "metabolic memory" of persistent vascular complications.


Novavax has begun a phase III trial of its SARS-CoV-2 vaccine, according to the New York Times.

The governor of New York says the state will conduct its own review of any SARS-CoV-2 vaccine, NPR reports.

Vox reports that the Trump Administration may limit student visas for individuals from some countries to two years.

This week in Science: Neanderthal Y chromosomes replaced by Homo sapiens Y chromosomes, and more.