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diabetes

In PLOS this week: cell-free DNA from tumors is shorter than DNA from healthy cells, type 2 diabetes-related loci, and more.

University of Wisconsin researchers uncover a mutation linked to Mauriac syndrome, which affects some children with type 1 diabetes.

In Nature this week: rare variants contribute little risk to type 2 diabetes, atlas of gene expression in developing primate brain, and more.

Genomic data for more than 125,000 individuals uncovered type 2 diabetes risk variants, many appearing at loci identified through common variant association studies.

The researchers plan to use the award to improve upon existing approaches to analysis of longitudinal proteomics data in the context of type I diabetes.

In the study, the partners will perform exome sequencing and whole-genome array genotyping on more than 9,000 individuals with diabetes or with diabetic relatives.

The investment, which will be paid out over the course of five years, comes in part from industry sources.

The portal offers access to genotype, phenotype, and clinical data related to type 2 diabetes as well as computational tools for querying the information. 

In PNAS this week: ties between epigenetic changes and metabolic memory, dromedary domestication patterns, and more.

Initially studying pancreatic tissue, the team also linked their findings to methylation patterns in blood, suggesting the possibility of developing a non-invasive test.

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Novavax has begun a phase III trial of its SARS-CoV-2 vaccine, according to the New York Times.

Vox reports that the Trump Administration may limit student visas for individuals from some countries to two years.

The governor of New York says the state will conduct its own review of any SARS-CoV-2 vaccine, NPR reports.

This week in Science: Neanderthal Y chromosomes replaced by Homo sapiens Y chromosomes, and more.