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diabetes

In Genome Research this week: post-zygotic mutations in diabetes development, single-cell RNA sequencing study of aging, and more.

A prospective metagenomic sequencing study searched for viral changes in children who developed islet autoimmunity or type 1 diabetes, revealing coxsackievirus ties to autoimmunity.

University of Virginia researchers are exploring a genetic risk test to gauge type 1 diabetes risk, NPR reports.

The researchers said the test performed well in distinguishing patients with or without complications and proved itself better than frequently used clinical variables.

Researchers linked 16 genetic loci to diabetic kidney disease, including a common missense mutation in the COL4A3 gene that appears to be protective.

In PNAS this week: C2CD4A gene involved in insulin secretion, chromosome rearrangements in recurring S. aureus infections, and more.

A Mendelian randomization analysis found visceral fat to be linked to cardiometabolic disease risk, especially type 2 diabetes risk in women.

In PLOS this week: gene variant may protect against trypanosomiasis, GLIS3 role in type 2 diabetes, and more.

At constant exchange rates, diagnostics revenues were up 2 percent, primarily due to the immunodiagnostics business.

The test combines a genetic risk analysis with behavioral and lifestyle assessments, and uses  Thermo Fisher Scientific's TaqMan OpenArray for genotyping.

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The Washington Post reports that a Russian Academy of Sciences commission has led to the retraction of hundreds of scientific papers.

The Los Angeles Times' Daily Pilot reports the chief executive of Vantari Genetics has pleaded guilty in a kickback scheme.

News 4 Jax reports that a Florida bill to prevent life and long-term care insurers from using genetic information in their coverage decisions has easily passed one committee.

In Science this week: potentially pathogenic mutations found in hematopoietic stem cells from young healthy donors, and more.