diabetes

A null mutation in the SERPINE1 gene was associated with longer telomeres and increased longevity among carriers, a new study found.

With exome and/or RNA sequences for dozens of insulinomas, researchers saw epigenetic, development, and other pathways prompting insulin-producing cell expansion.

The researchers believe that the discovery of the genetic loci linked to T2D and CHD will lead to therapeutic opportunities to lower the risk of both diseases.

Startups offering blockchain technology to support genomics and precision medicine still need to prove themselves and find markets.

The newly announced Microbiome Immunity Project seeks to discover links between autoimmune diseases and bacteria in and on the human body.

The collaboration will place T1D in the field of precision medicine, potentially allowing JDRF to identify factors that potentially lead to T1D.

On a conference call, the firm's CEO said that it and other industry players are pushing to postpone implementation of PAMA to no earlier than July 1, 2018. 

Using small RNA sequencing, investigators found miRNAs in the blood that track with cirrhosis, hepatitis, type 2 diabetes, or acetaminophen toxicity.

This Week in Science

In Science this week: a protective gene in C. elegans, and combining EHRs with genetic data to ID HLA-associated variants

The researchers noted that 93 of the newly identified loci are found in both African-American and European populations, and only 18 are European-specific.

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The US Food and Drug Administration has new guidelines that enable some gene and cell therapies to undergo expedited review, according to the New York Times.

Using gene drives to control invasive species might be too risky, an initial advocate of the approach says.

Researchers have grown tumors in 3D cell cultures to better understand cancer, the Economist reports.

In Science this week: intellectual property experts argue patent battles such as the one over CRISPR are wasteful, and more.