diabetes
Type 2 Diabetes Mechanisms, Risk Genes Identified in GWAS Meta-Analysis
Researchers uncovered candidate risk genes and potential mechanisms and conducted further analyses of proinsulin-associated risk loci.
Exome Sequencing Study Identifies Potential Treatment Target for Diabetes
Individuals with protein-truncating MAP3K15 variants are less likely to develop diabetes, suggesting it could also be a possible target for managing the disease.
Diabetes Polygenic Risk Score Performance Improved by Addition of Rare Variants
Researchers found that rare variants linked to type 2 diabetes or related traits can bolster diabetes classifications performed using common variant polygenic risk scores.
Genomics PLC to Provide Polygenic Risk Scores for UK's Our Future Health Research Program
The company will work in partnership with Our Future Health to generate risk scores for up to 5 million people and to create methods for providing feedback to participants.
Family History Improves Polygenic Risk Scores for Complex Disease in Non-Europeans
Strategies for predicting complex disease risk with both polygenic and family history clues appeared beneficial for non-European individuals.