A prospective metagenomic sequencing study searched for viral changes in children who developed islet autoimmunity or type 1 diabetes, revealing coxsackievirus ties to autoimmunity.
The researchers said the test performed well in distinguishing patients with or without complications and proved itself better than frequently used clinical variables.
The test combines a genetic risk analysis with behavioral and lifestyle assessments, and uses Thermo Fisher Scientific's TaqMan OpenArray for genotyping.
In Science this week: approach to measure microRNA targeting efficiency, strategy to conduct high-throughput chemical screens at single-cell resolution, and more.
