diabetes Diabetes Subtypes Stem From Distinct Genetic Contributors, Study Suggests Researchers described five diabetes clusters with specific clinical features that corresponded to different genetic contributors, genetic risk scores, and family history patterns. Broad Institute, Novo Nordisk Foundation Launch Center to Study Genomic Mechanisms of Disease The center, which is being funded by a $47.5 million commitment from the foundation, will initially focus on type 2 diabetes and obesity. Rare Mutations Associated With Significantly Higher Risk of Type 2 Diabetes in New Study University of Cambridge and Broad Institute researchers found what could be a direct connection between clonal mosaicism and metabolic health. Type 1 Diabetes GWAS, Fine-Mapping Leads to New Genetic Loci, Potential Drug Targets Starting with a large GWAS, researchers incorporated chromatin accessibility data and other clues to find key variants, immune cell types, and treatment targets. GWAS Across Ancestries Uncovers Novel Genetic Loci Linked to Glycemic Traits The researchers estimated that if their analysis had only focused on individuals of European descent, they would have missed two dozen novel loci. Apr 27, 2021 Syntegra Teams With Vanderbilt's Nashville Biosciences on Biobank Data Analysis for Drug R&D Mar 31, 2021 Type 1 Diabetes Onset Preceded by Gene Expression Changes Mar 5, 2021 Fauna Bio Gets $373K NIH Grant to Study Animal Genomes for Potential Drug Targets Feb 11, 2021 Global, Local Polynesian Ancestry Influence Disease Risk Among Native Hawaiians Jan 19, 2021 Blood, Urine Biomarker Study Leads to Linked Loci, Disease-Related Risk Scores Oct 7, 2020 Patia Biopharma, Precision Diabetes to Collaborate on Diabetes Biomarker Development Sep 16, 2020 Epigenetic Markers Predict Type 2 Diabetes Patients Who Respond to, Tolerate Metformin Jul 10, 2020 Prediabetes, Type 2 Diabetes Come With Altered Gut Microbiomes Jul 7, 2020 Exome Analysis of Southwestern American Indians Highlights Metabolic Disease-Linked Variants Jul 2, 2020 Type 2 Diabetes Associated With Altered Daily Gut Microbe Oscillations Jun 24, 2020 Two Polycystic Ovary Syndrome Subtypes Emerge From Phenotypic Clustering Analysis Premium Jun 16, 2020 Multi-Ancestry Type 2 Diabetes Genetic Study Discovers Hundreds of Novel Loci Jun 12, 2020 RenalytixAI Receives Approval From New York State to Offer Kidney Test May 6, 2020 GWAS Meta-Analysis of East Asian Individuals Link 60 New Loci to Diabetes Risk Apr 22, 2020 Roche Diagnostics Q1 Sales Essentially Flat Mar 16, 2020 With $100M in New Funding, Tempus Targets Diseases Beyond Cancer Premium Mar 13, 2020 Tempus Closes $100M Series G Round Feb 13, 2020 Type 2 Diabetes Risk for Women With Gestational Diabetes is Increased by Genetic Factors Dec 2, 2019 Longitudinal Stool Sampling Study Points to Virome Shifts in Children With Islet Autoimmunity Oct 2, 2019 Liquid Biopsy Test Targets Early Detection of Diabetes Complications, Cancers Premium Load More Breaking News Pediatric Cardiomyopathy Exome Sequencing Study Suggests More Disease Genes to be Found People in the News: New Appointments at Helix, Pacific Biosciences, SomaLogic, More New Products Posted to GenomeWeb: Amoy Diagnostics, Akoya Biosciences, Congenica, Lucence In Brief This Week: BGI, Gencove, Cepheid, Biocartis, Biognosys, Co-Diagnostics, More Florida Lab Owner Pleads Guilty to $6.9M COVID-19 False Billing Scheme Pacific Biosciences Outlines Progress on Short-Read Sequencing at JPM, Partners With Canexia Health The Scan Close Panel Vote on Califf Nomination The New York Times reports there was a close committee vote to advance the nomination of Robert Califf to lead the US Food and Drug Administration to the full Senate. Task Force Reports on Scientific Integrity Nature News writes that that a new task force report recommends that the US establish a cross-agency scientific integrity council. Across the Hall Genetic testing, closed-circuit cameras, and more show how a traveler, without any contact, infected others at a New Zealand quarantine facility, CNN reports. Science Paper Examines Influence of Chromatin Modifications on Obsessive-Compulsive Disorder In Science this week: genes regulating chromatin modification may contribute to OCD risk.