In analyses of multiple traits and diseases, investigators uncovered loss-of-function or truncating changes with apparent protective effects.
The team used genetic scoring to identify infants without a family history of the disease who had more than a 10 percent risk for developing islet antibodies.
In PLOS this week: tick salivary transcriptome, genetic risk scores for type 1 diabetes, and more.
Using data for thousands of Chinese individuals, researchers saw new and known variants associated with type 2 diabetes, fasting glucose levels, and other metabolic traits.
With the help of electronic health record data, researchers searched for common variants linked to hundreds of diseases or clinical lab measurements.
In Science this week: gut bacteria that influence effectiveness of a high-fiber diet in type 2 diabetes, and more.
Researchers found methylation mediators of obesity and other metabolic features by profiling individuals born after a famine called the Dutch Hunger Winter.
Family members with diabetes and others with insulinomatosis both harbor the same missense MAFA mutation.
In Nature this week: a genomics search engine, and more.
The funding will support further development of an existing serum-based assay and expansion of the test to use saliva samples.
Researchers have sequenced the northern white rhinoceros to gauge whether it could be brought back from the edge of extinction, the New York Times reports.
Bavaria expands its forensic genetic analyses to include DNA phenotyping, raising discrimination concerns.
Tufts University researchers found a role for miRNA in transmitting stress between generations, the Economist reports.
In Science this week: gut microbiome influences liver cancer growth, spread; and more.