depression Large-Scale Depression Genetic Study Uncovers Additional Risk Loci, Ties to Potential Drugs The analysis drew upon data from the Million Veteran Program and other large-scale efforts and underscores the genetic complexity of depression. Proteome-Wide Association Study of Depression Homes in on Potential Treatment Targets The researchers uncovered 25 brain proteins that appear to contribute to depression, of which 20 were not previously implicated in the condition. Case-Case GWAS Approach Identifies Loci That Differ in Frequency Across Psychiatric Disorders The approach provides new insights into genetic differences between various disorders in order to improve their diagnosis and treatment. Psychiatric Disorder Risk Affected by Dysregulation of RNA-Binding Proteins Using a deep learning approach to study mutations in target sites of RNA-binding proteins, researchers identified DDHD2 as a candidate schizophrenia risk gene. Depression-Related Gut Microbiome, Metabolite Changes Lead to Potential Biomarker Set Metagenomic sequencing and fecal metabolite profiling uncovered major depressive disorder-related gut microbe changes and a combinatorial marker set. Dec 2, 2020 Genetic Technologies Lands Distribution Rights to Taliaz Antidepressant Drug Selection Tools May 14, 2020 Brain Proteins May Mediate Effects of Genetic Variants on Some Neurological Phenotypes Apr 15, 2020 Childhood Mood, Behavioral Problems May Share Genetic Features With Some Adult Conditions Mar 30, 2020 Depression GWAS Based on Minimal Phenotyping May Lead to Skewed Results Mar 16, 2020 With $100M in New Funding, Tempus Targets Diseases Beyond Cancer Premium Mar 13, 2020 Tempus Closes $100M Series G Round Jan 8, 2020 Psychiatric Disorders, Body Mass Index Share Genetic Loci, Study Finds Dec 12, 2019 Psychiatric Disorders Fall Into Groups With Shared Genetic Contributors in GWAS Meta-Analysis Nov 21, 2019 Intermountain Healthcare to Gather Utility Data as SelectHealth Covers PGx Test for Certain Employees Premium Sep 26, 2019 Mental Health Advocacy Groups Appeal to FDA to Reconsider PGx Enforcement Activity Sep 25, 2019 Genetic Links Between Psychotic Experiences, Neuropsychiatric Diseases Uncovered in Study Aug 1, 2019 Myriad Genetics GeneSight PGx Test Garners UnitedHealthcare Coverage Jun 20, 2019 On Heels of $200M Cash Infusion, Tempus Enters Major Growth Phase Premium Jun 5, 2019 NIH Announces Upcoming Genomic Medicine Studies May 30, 2019 Tempus Raises $200M in Series F Financing Apr 16, 2019 Ancient European, Pathogen DNA Data Promises to Shed Light on Brain Disorders, Infectious Disease Premium Feb 25, 2019 Autism Spectrum Disorder GWAS Highlights Common Risk Variants, Overlap With Other Conditions Feb 6, 2019 Schizophrenia, Depression Studies Suggest Gut Microbiome May Influence Mental Health Feb 5, 2019 Depression GWAS Meta-Analysis Uncovers New Loci, Potential Drug Targets Jan 30, 2019 Polygenic Risk Scores for Three Psychiatric Disorders Linked to Depression Diagnoses Load More Breaking News Enzo Biochem, CLX Health Partner to Support COVID-19 Testing for International Travel Type 1 Diabetes GWAS, Fine-Mapping Leads to New Genetic Loci, Potential Drug Targets LSU Health Sciences Center Wins $2.4M to Lead SARS-CoV-2 Variant Sequencing Program NanoString Technologies, Parker Institute for Cancer Immunotherapy Partner on Cell Therapy Project BGI Americas Collaborating With Champions Oncology on Proteomic Cancer Research Personal Genome Diagnostics Inks Cancer Genomic Profiling Deal with Duke University Health System The Scan Missed Early Cases A retrospective analysis of blood samples suggests early SARS-CoV-2 infections may have been missed in the US, the New York Times reports. Limited Journal Editor Diversity A survey finds low diversity among scientific and medical journal editors, according to The Scientist. How Much of a Threat? Science writes that need for a provision aimed at shoring up genomic data security within a new US bill is being questioned. PNAS Papers on Historic Helicobacter Spread, Brain Development, C. difficile RNAs In PNAS this week: Helicobacter genetic diversity gives insight into human migrations, gene expression patterns of brain development, and more.