Using a deep learning approach to study mutations in target sites of RNA-binding proteins, researchers identified DDHD2 as a candidate schizophrenia risk gene.
The products analyze various datasets including a patient's genetic and metabolic profiles, clinical history, and demographics to inform prescribing decisions.
In PNAS this week: similar muscle protein patterns across hypertrophic cardiomyopathy phenotypes, analysis of gene expression and brain anatomy in major depression, and more.
The study also found that certain genes may influence multiple complex traits, while others only affect one phenotype, making them worthwhile therapeutic targets.
An analysis of almost 43,000 individuals under 17 years suggests polygenic scores for adult conditions such as depression may coincide with childhood psychopathology.
A new study showed that relying on minimal phenotyping could impede researchers' ability to identify genetic pathways specific to major depressive disorder.
The New York Times reports that experts say President Joe Biden's goal of vaccinating 1 million people a day in the US in the next 100 days is too low a bar.
