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In PNAS this week: similar muscle protein patterns across hypertrophic cardiomyopathy phenotypes, analysis of gene expression and brain anatomy in major depression, and more.

In PLOS this week: phenome-wide association study of psychiatric disorder polygenic risk scores, CNV patterns in rhesus macaques, and more.

The study also found that certain genes may influence multiple complex traits, while others only affect one phenotype, making them worthwhile therapeutic targets.

As Kids and Adults

Cosmos reports that people who are at genetic risk of developing depression as adults are also more likely to have problems as children.

An analysis of almost 43,000 individuals under 17 years suggests polygenic scores for adult conditions such as depression may coincide with childhood psychopathology.

A new study showed that relying on minimal phenotyping could impede researchers' ability to identify genetic pathways specific to major depressive disorder.

The precision medicine company also is accelerating its push into diabetes, depression, and cardiology after getting its solid-tumor test turnaround down to 9 days. 

Now valued at $5 billion, the company will apply the new funding to continue its expansion in diabetes, depression, and cardiology. 

Some of these shared loci were associated with higher BMI, but some were linked to lower BMI, particularly those also linked to schizophrenia.

A genome-wide association study meta-analysis of eight psychiatric conditions led to new and known risk loci, and revealed three distinct groups of conditions.

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Novavax has begun a phase III trial of its SARS-CoV-2 vaccine, according to the New York Times.

Vox reports that the Trump Administration may limit student visas for individuals from some countries to two years.

The governor of New York says the state will conduct its own review of any SARS-CoV-2 vaccine, NPR reports.

This week in Science: Neanderthal Y chromosomes replaced by Homo sapiens Y chromosomes, and more.