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depression

Startup Circular Genomics Raises $4.5M in Seed Funding

The company was founded earlier this year to commercialize a test for depression based on circular RNA biomarker technology.

Analysis Estimates Psychiatric Disorder Risk from Specific Copy Number Variants in Danish Cohort

The population-based analysis found that deletions and duplications in six genomic loci generally increased risk for autism spectrum disorder and ADHD.

Pharmacogenomics Firm Genetika+ Raises $10M in Series A Round

The company is developing a test to predict the best antidepressant drug or drug combination for a specific patient.

Large-Scale Depression Genetic Study Uncovers Additional Risk Loci, Ties to Potential Drugs

The analysis drew upon data from the Million Veteran Program and other large-scale efforts and underscores the genetic complexity of depression.

Proteome-Wide Association Study of Depression Homes in on Potential Treatment Targets

The researchers uncovered 25 brain proteins that appear to contribute to depression, of which 20 were not previously implicated in the condition.

Mar 8, 2021

Case-Case GWAS Approach Identifies Loci That Differ in Frequency Across Psychiatric Disorders

Jan 19, 2021

Psychiatric Disorder Risk Affected by Dysregulation of RNA-Binding Proteins

Dec 2, 2020

Depression-Related Gut Microbiome, Metabolite Changes Lead to Potential Biomarker Set

Dec 2, 2020

Genetic Technologies Lands Distribution Rights to Taliaz Antidepressant Drug Selection Tools

May 14, 2020

Brain Proteins May Mediate Effects of Genetic Variants on Some Neurological Phenotypes

Apr 15, 2020

Childhood Mood, Behavioral Problems May Share Genetic Features With Some Adult Conditions

Mar 30, 2020

Depression GWAS Based on Minimal Phenotyping May Lead to Skewed Results

Mar 16, 2020

With $100M in New Funding, Tempus Targets Diseases Beyond Cancer
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Mar 13, 2020

Tempus Closes $100M Series G Round

Jan 8, 2020

Psychiatric Disorders, Body Mass Index Share Genetic Loci, Study Finds

Dec 12, 2019

Psychiatric Disorders Fall Into Groups With Shared Genetic Contributors in GWAS Meta-Analysis

Nov 21, 2019

Intermountain Healthcare to Gather Utility Data as SelectHealth Covers PGx Test for Certain Employees
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Sep 26, 2019

Mental Health Advocacy Groups Appeal to FDA to Reconsider PGx Enforcement Activity

Sep 25, 2019

Genetic Links Between Psychotic Experiences, Neuropsychiatric Diseases Uncovered in Study

Aug 1, 2019

Myriad Genetics GeneSight PGx Test Garners UnitedHealthcare Coverage

Jun 20, 2019

On Heels of $200M Cash Infusion, Tempus Enters Major Growth Phase
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Jun 5, 2019

NIH Announces Upcoming Genomic Medicine Studies

May 30, 2019

Tempus Raises $200M in Series F Financing

Apr 16, 2019

Ancient European, Pathogen DNA Data Promises to Shed Light on Brain Disorders, Infectious Disease
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Feb 25, 2019

Autism Spectrum Disorder GWAS Highlights Common Risk Variants, Overlap With Other Conditions

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The Scan

And a Fourth?

A fourth dose of the Pfizer-BioNTech SARS-CoV-2 vaccine in an Israeli study increased antibody levels but did not prevent Omicron variant infections, according to the Financial Times.

For Better Science Software

A virtual institute funded by former Google CEO Eric Schmidt's philanthropy aims to lure software engineers to academia, Science reports.

Recommendation Explanations

The New York Times writes that the US Centers for Disease Control and Prevention is straining to both make and explain decisions based on limited information.

Genome Research Papers on De Novo Mutation Rates, Polyploid Genotyping, Oncogene Epigenomic Translocation

In Genome Research this week: de novo mutations rates in hemoglobin subunits, analysis of variant calling methods for polyploid plants, and more.