dementia
Dementia Contributors Uncovered Using Neuropathy Endophenotype-Focused Strategies
Researchers defined 11 neuropathy endophenotypes, using genome-wide association and functional approaches to pinpoint related variants, expression patterns, and methylation shifts.
Constantiam Bio Gets $485K Grant From National Institute on Aging for Alzheimer's Tool Development
The funding will be used to advance a tool for interpreting risk variants associated with Alzheimer’s disease and related dementias.
Dementia Prediction Biomarkers Pinpointed in Plasma Proteomics Study
Researchers flagged a handful of proteins in the blood of UK Biobank participants that correlated with their risk of later developing dementia.
As part of a pilot project for the NIH CARD initiative, researchers used large-scale nanopore sequencing to study the genetics of Alzheimer’s disease.
APOE Missense Variant Linked to Increased Alzheimer's Disease Risk in African Americans
A case-control study found that the APOE ε3[R145C] variant, seen in 4 percent of African Americans, increases AD risk in individuals with the ε3/ε4 genotype.