Using data for almost 10,900 Latino individuals with diverse ancestry, investigators identified distinct patterns for risky or protective APOE variants.
The assay was shown to have a simpler workflow and was able to detect mosaicism, with only a slight decrease in sensitivity compared to a lab-developed test.
Using large-scale GWAS data, researchers saw shared genetic contributors for ALS and frontotemporal dementia, as well as ALS and progressive supranuclear palsy.
Speakers at HudsonAlpha's Genomic Medicine Conference said while sequencing results sometimes result in a diagnosis and change in care, they often have no consequence.
The startup was cofounded by the Broad Institute's Feng Zhang and Harvard's David Walt among others, and raised $15.6 million in June.
Based on their genome-wide association study, investigators argued that the dementia condition is not simply an extension of Alzheimer's or Parkinson's disease.
Researchers saw partial overlap between variants influencing age-related methylation and neuronal patterns and those implicated in other traits or diseases.
The firm is leveraging its broad network and deep diagnostics test portfolio to provide integrated solutions around clinical problems.
The companies said they aim to discover next-generation tests that will enable early diagnosis of dementia, as well as treatment selection and monitoring.
Five research teams from the University of British Columbia and Simon Fraser University will split the funding.
Researchers in France have explored the genetic history of the blue cheese mold, Forbes reports.
The South China Morning Post reports eight genetic testing firms in Hong Kong are under scrutiny for potentially misleading consumers.
In Science this week: platform to diagnose genetic disease in children, lung disease-causing genetic mutation corrected in mice, and more.
Wired reports on how genetic genealogy's use in forensics has exploded in the year since an arrest in the Golden State Killer case was made.