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Crohn's disease

The test is made up of six serologic markers and three genetic mutation markers.

By amalgamating data from several past genome-wide association studies, an international research team has nearly doubled the number of genetic loci linked to Crohn's disease.

The companies aim to identify genetic and serologic biomarkers for use in predicting response to treatments such as Cimzia, Humira, and Remicade, and to develop diagnostics based on the biomarkers.

Agilent's Human CNV Association 2x105K microarray, based on a design by the Wellcome Trust Case Control Consortium, is the company's second catalog CNV chip and was designed for studying associations between genomic CNVs and disease.

Shire Owings Mills (Md.) Plant, Alexandria Real Estate Equities, Takeda Pharmaceutical, Wareham Development, PATH, Fall River (Mass.) Executive Park, University of Massachusetts/Dartmouth Bioprocessing Facility, Silicon Border, Sapphire Engineering, Campanelli Business Park, University of California-Davis M.I.N.D., Institute, Doe & Ingalls of North Carolina, Covaris, Life Technologies, BioMed Realty Trust, Shasun Pharma Solutions

Having site-specifically labeled human annexin V, the two companies are now developing an imaging biomarker to evaluate responses to anti-inflammatory and oncology therapies.

The company also noted in a filing with the US Securities and Exchange Commission that it continues to seek out industry partnerships after having failed to forge a deal in 2008 as previously anticipated.

HHMI and University of Washington researcher Evan Eichler led a team of researchers who found evidence suggesting a gene called IRGM became a pseudogene in the ancestor of monkeys and apes before being resurrected in the human-great ape lineage.

Sylentis will perform the initial clinical trial on its own in Spain for logistical reasons, but expects to later test the topically administered drug in other countries, including the US, according to a company official.

Based on their assessment of SNP data for several complex diseases, researchers from the University of Pittsburgh and the University of California at Los Angeles warn that genetic tests based on existing GWAS may not be refined enough to accurately predict individual disease risk.

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An initial analysis suggests the novel coronavirus from Wuhan that is sickening people might come from snakes, a team of virologists writes at the Conversation.

DNA testing confirms captured Chicago coyote same as the one that bit a boy near a nature museum, the Chicago Tribune reports.

An analysis of Tibetan ice cores uncovers more than two dozen previously unknown virus groups, LiveScience reports.

In Nature this week: genomic analysis of four children buried in Cameroon approximately 3,000 and 8,000 years ago, and more.