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Crohn's disease

NEW YORK (GenomeWeb News) –Genisphere and the Lankenau Institute for Medical Research today said that they have expanded their research collaboration aimed at identifying microRNA biomarkers to include Crohn's Disease and other inflammatory bowel disorders.

BRB, which is also developing similar tests for other cancers and autoimmune diseases, has partnered with lab testing services firm Clinical Reference Laboratory for clinical validation of its tests.

The test is made up of six serologic markers and three genetic mutation markers.

By amalgamating data from several past genome-wide association studies, an international research team has nearly doubled the number of genetic loci linked to Crohn's disease.

The companies aim to identify genetic and serologic biomarkers for use in predicting response to treatments such as Cimzia, Humira, and Remicade, and to develop diagnostics based on the biomarkers.

Agilent's Human CNV Association 2x105K microarray, based on a design by the Wellcome Trust Case Control Consortium, is the company's second catalog CNV chip and was designed for studying associations between genomic CNVs and disease.

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Having site-specifically labeled human annexin V, the two companies are now developing an imaging biomarker to evaluate responses to anti-inflammatory and oncology therapies.

The company also noted in a filing with the US Securities and Exchange Commission that it continues to seek out industry partnerships after having failed to forge a deal in 2008 as previously anticipated.

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Researchers have developed a robotic lab assistant, the Verge reports.

CBC News reports Canada's Supreme Court is to rule on the constitutionality of the country's genetic non-discrimination law today.

The Associated Press reports the World Health Organization is sending experts to China to investigate the animal source of SARS-CoV-2.

In Science this week: atlas of affected cell populations in idiopathic pulmonary fibrosis, and more.