Crohn's disease Adaptive Biotech Touts Progress Toward Lyme and Gastrointestinal Disease Diagnostics Premium The firm is expanding its plans from a Crohn's disease test to a broader GI differential diagnostic and continues to expect to launch its Lyme disease assay by year-end. Inflammatory Bowel Disease Genetic Risk Architecture Appears Distinct in African Americans Using whole-genome sequence data for thousands of African American individuals, researchers teased out ancestry effects on polygenic risk of the conditions. ABO Histo-Blood Groups Influence Makeup of Gut Microbiome, New Study Finds The findings further suggested the gut microbiome could influence conditions like inflammatory bowel disease and serve as therapeutic targets. IBD Polygenic Risk Scores Improved With Data From Multiple Ancestral Backgrounds The researchers also examined the contribution of rare variants to inflammatory bowel disease to find a potential targetable pathway. Single-Cell Transcriptome Study Links Gut Development, Pediatric Crohn's Disease Researchers saw transcription factor similarities between developing human intestinal cells and cells from pediatric Crohn's disease cases. Nov 11, 2020 Adaptive Biotechnologies Prepares to Launch T Cell-Based COVID-19 Test Premium Jul 21, 2020 Inflammatory Bowel Disease Study Points to Role For Somatic Colon Mutations Jul 13, 2020 Genuity Science, Formerly WuXi NextCode, Reinvents Itself With US, Europe Focus Premium Jul 1, 2020 Celsius Therapeutics Teams With Oxford, Cleveland Clinic, LMU on Single-Cell IBD Research Mar 5, 2020 Genedata Moves Into R&D for Nonprofits, Adds Digital Pathology Support Premium Jan 21, 2020 PredictImmune Inks Multinational Commercialization Pact for IBD Test Nov 7, 2019 PredictImmune, Crohn's & Colitis Foundation Collaborate on IBD Test Validation Study Oct 25, 2019 Helmsley Foundation Awards $13M in Grants for Gut Cell Atlas Oct 22, 2019 KSL Biomedical to Commercialize PredictImmune IBD Test in North America Sep 19, 2019 PredictImmune Expands Licensing Deal With Cambridge Enterprise Apr 2, 2019 PredictImmune, Addenbrooke's Hospital Sign Agreement to Provide IBD Diagnostic in UK, Ireland Mar 6, 2019 Inflammatory Bowel Disease Transcriptome Analysis Finds Increased Levels of SERPINE1 Feb 26, 2019 New IBD Adverse Drug Response Risk Gene Identified Dec 13, 2018 PredictImmune Wins £100K Grant for Study of IBD Prognostic Dec 11, 2018 PredictImmune Gains CE-IVD Mark for IBD Test Oct 5, 2018 Crohn's Disease MicroRNA Marks Subtypes With Differing Outcomes Sep 18, 2018 Prescient Medicine, Metabiomics Form GI Dx Partnership May 4, 2018 PredictImmune Plans 2019 European, US Launches for qPCR-Based Crohn's Biomarker Test Premium Apr 30, 2018 PredictImmune Receives £4.3M From Wellcome Trust for Crohn's Biomarker Study Jan 10, 2018 Crohn's, Parkinson's Diseases Share Risk Gene Load More Breaking News Ancient DNA Analysis Highlights Three Ancestral Populations in Japan FDA Warns of Potential False Positives With Abbott SARS-CoV-2 Molecular Tests New Products Posted to GenomeWeb: Oxford Nanopore, Beckman Coulter, Thermo Fisher Scientific, More People in the News: New Appointments at Sema4, NHGRI, Dante Labs, Ancestry, More Thermo Fisher Scientific Expects 12 Percent Revenue Growth in 2022 In Brief This Week: Myriad Genetics, Danaher, Co-Diagnostics, and More The Scan For Those Thick Tiger Stripes Tigers in India with thick stripes harbor a genetic change, as Gizmodo reports. High GABA Tomatoes The Japan News reports that genome-edited tomatoes with higher GABA levels are now for sale in Japan. Approach for Inclusivity and Diversity A National Human Genome Research Institute team calls for the field to "adopt diversity as an ethos." Science Papers on Tumors Immune System Evasion; Drivers of Genomic Instability, Inflammation In Science this week: study of how tumors evade the adaptive immune system, and more.