Crohn's disease

The newly announced Microbiome Immunity Project seeks to discover links between autoimmune diseases and bacteria in and on the human body.

A team has identified disease loci for Crohn's and ulcerative colitis using fine mapping alongside high-density genotyping. 

The model incorporates clinical, serological, and gene expression factors, and could be used to tailor treatment choices.

A genome-wide association study of more than 2,700 individuals with Crohn's disease uncovered prognosis-related loci distinct from those linked to disease risk.

Based on genetic patterns in thousands of individuals with primary sclerosing cholangitis, researchers identified four new risk loci and explored ties to IBD.

In colon tissue samples from individuals with Crohn's disease, researchers discovered either colon- or ileum-like expression features.

A team of scientists and entrepreneurs is trying to build a company around a dataset from a large multi-omics clinical study funded by Genome Canada.

Researchers used genomic approaches to search for disease clues in purified cells from ileum or colon biopsies of pediatric inflammatory bowel disease patients.

IQuity's current tests analyze gene expression patterns detected in mRNA, but the firm is also exploring the diagnostic potential of long non-coding RNAs.

Using genotyping data, the Children's Hospital of Philadelphia-led team found high heritability across pediatric-onset autoimmune diseases.

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A former Synthetic Genomics attorney alleges that the firm discriminated against her and other female employees, according to the San Diego Union-Tribune.

Due to privacy and lab certification questions, the planned giveaway of Orig3n testing kits at a Baltimore Ravens game was suspended.

Alnylam reports positive results from its phase 3 clinical trial of an RNAi-based drug, according to Stat News.

In Cell this week: adult mesenchymal cell populations in mouse lung, genetic diversity in HPV16 and cancer risk protection, and more.