Crohn's disease
Wellcome Sanger Institute, Pacific Biosciences Collaborate on Immune Cell Gene Expression Profiling
Sanger researchers will apply long-read single-cell RNA sequencing at scale for the first time in the project, which receives financial support from PacBio.
'Living Organoid' Biobank Helps Uncover Crohn's Disease Molecular Subtypes, Therapeutic Leads
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UCSD researchers discovered two transcriptionally distinct molecular subtypes of Crohn's disease and are developing a candidate therapy for each.
Wellcome Sanger Institute, Open Targets Fund Inflammatory Bowel Disease Biomarker Study
Researchers will analyze multiomic and clinical data from 1,000 patients with IBD recruited from seven participating hospitals in the UK.
Inflammatory Bowel Disease Genetics Understanding Expands With East Asian Analyses
A genome-wide association study and meta-analysis of tens of thousands of East Asian participants led to new genetic contributors to Crohn's disease and ulcerative colitis.
The CDPath prognostic tool gives Crohn's patients risk scores for serious complications within three years, so they can make more informed treatment decisions.