Quest, which plans to acquire Celera by the end of the month, could provide the financial backing to conduct prospective studies for the KIF6 test, or it could decide to scrap the KIF6 program altogether.
In a trio of papers appearing online yesterday in Nature Genetics, several large research teams describe efforts to track down new coronary artery disease risk variants in European, South Asian, and Han Chinese populations.
"Going forward, the KIF6 story should serve as a valuable reminder of the potential pitfalls present in prematurely adopting a genomic test without sufficient evidence," according to an editorial accompanying the study.
Members of the "Coronary Artery Disease Genome-Wide Replication and Meta-Analysis" study are bringing together data from published and unpublished genome-wide studies of heart attack and coronary artery disease to find previously undetected risk variants in individuals of European descent.
OSU Medical Center will enroll patients who agree to join Coriell's personalized medicine project under the guidance of their primary care physician. The partners will study the impact of using genomic information in treating chronic conditions.