coronary artery disease

UK and Swedish researchers used a Mendelian randomization approach to study the association between serum calcium and heart disease and heart attack risk.

Using data from the UK Biobank, a Harvard Medical School-led team of researchers has uncovered 15 new loci associated with coronary artery disease.

The international team says its findings may explain the evolutionary reasons for the maintenance of coronary artery disease in human populations.

Researchers found that certain somatic mutations in blood stem cells elevate coronary heart disease risk, likely by accelerating atherosclerosis.

The test is the first offered for the Sgx Clarity system, a fully automated in vitro diagnostic platform leveraging single-molecule counting technology.

The team performed a gene expression analysis to discover the new loci, bringing the total number of known risk loci associated with CAD to 73.

By studying variants in PCSK9, researchers reported the therapies targeting the gene would have some of the same effects as statins.

The results of this meta-analysis by University of Cambridge-led team could have implications for LDL-C-lowering therapies.