Using data from the UK Biobank, researchers explored relative contributions that genetics and lifestyle make to cardiovascular disease and diabetes risk.
Analyzing samples from Iceland and elsewhere, researchers uncovered one known and two new risk loci for aortic valve stenosis that are also associated with other heart risk pathways.
Investigators came up with a 182-variant risk score for early-onset coronary artery disease, which they tested on SNP data from UK Biobank participants with or without the condition.
A pair of studies has uncovered additional loci and ancestry-specific variants that are associated with plasma lipid levels and coronary artery disease risk.
A Johns Hopkins team reported its finding in JAMA Cardiology, backed by SNP array data from 21,870 participants culled from several large cardiovascular studies.
Researchers found variants associated with coronary artery disease and migraine risk at three loci in a genome-wide association study, with opposing directional effects at two index SNPs.
UK and Swedish researchers used a Mendelian randomization approach to study the association between serum calcium and heart disease and heart attack risk.
Using data from the UK Biobank, a Harvard Medical School-led team of researchers has uncovered 15 new loci associated with coronary artery disease.
The international team says its findings may explain the evolutionary reasons for the maintenance of coronary artery disease in human populations.
Researchers found that certain somatic mutations in blood stem cells elevate coronary heart disease risk, likely by accelerating atherosclerosis.
In a commentary at eLife, Brandeis University's Eve Marder calls on researchers to value and pursue truth.
Researchers have developed a way to quickly edit white blood cells, according to the New York Times.
In Science this week: rice gene enables plants to grow quickly in times of flooding, and more.
Education-linked genetic variants could also predict a small portion of a person's social mobility, Newsweek reports.