coronary artery disease University of Sydney Wins A$1.4M Grant, Teams With Allelica on Cardiac Polygenic Risk Scores Researchers at the University of Sydney will work with Allelica to develop polygenic risk scores for coronary artery disease prevention and integrate the testing into primary care. Invitae to Provide Genetic Testing Within eMERGE Population Screening Study As a new clinical affiliate, Invitae will test up to 25,000 patients in a study exploring the role of genetics in cancer, heart disease, and other conditions. Meta-Analysis Supports Pharmacogenomic Testing Prior to Anti-Platelet Therapy The study showed that CYP2C19 genotyping could help clinicians reduce ischemic events in patients with coronary artery disease by tailoring their treatment. Genomics Plc Looks to Grow 'Genomic Prevention' With Polygenic Risk Scores Premium In two recent papers, the UK startup demonstrated the integration of polygenic risk scoring into primary care screening and workflows. Coronary Artery Disease Loci Identified in Japanese GWAS, Trans-Ancestry Meta-Analysis Researchers found ancestry-specific risk variants and developed a better polygenic risk score based on a GWAS and subsequent meta-analysis. Sep 4, 2020 Complex Genetics Identified for Heart Condition Affecting Seemingly Healthy Young Women Jun 9, 2020 Large-Scale Japanese GWAS Uncovers Two Novel Loci Associated With Lung Cancer, Heart Disease Feb 18, 2020 Polygenic Risk Score Studies Suggest Conventional Heart Disease Prediction Methods Still Preferable Jan 16, 2020 DNAFeed Adds Genetic Counseling to Scripps Polygenic Risk Study Premium Dec 5, 2019 Polygenic Modifiers of Pathogenic Genes May Refine Disease Risk Prediction Premium Jul 29, 2019 Metabolic Syndrome, Early-Onset Coronary Artery Disease Linked to Mutations in CELA2A Apr 26, 2019 Gencove Wins $330K NIH Grant for Polygenic Risk Score Evaluation Tech Dec 20, 2018 Somalogic Using DeCode Deal to Drive Development of Clinical Proteomics Pipeline Premium Oct 16, 2018 Scripps Research Translational Institute, Seqster Partner to Engage Consumers on Heart Disease Risk Oct 4, 2018 Mendelian, Common Disease Links Detected From GWAS Data Sep 4, 2018 True Bearing Readies RNA-Based Coronary Artery Disease Diagnostic for FDA Review, Launch Premium Aug 13, 2018 Broad Institute, Mass General Team Develops Polygenic Risk Scores for Five Common Diseases Jun 27, 2018 Lifestyle, Genetics Independently Predict Cardiovascular Disease, Diabetes Risk Mar 7, 2018 Aortic Valve Stenosis GWAS Leads to Loci Also Tied to Heart Development, Atherosclerosis Jan 8, 2018 Polygenic SNP Score Correlates With Early-Onset Coronary Artery Disease Risk Oct 30, 2017 Two Studies Examine Loci Linked to Lipid Levels, Coronary Artery Disease Oct 12, 2017 Cardiovascular Disease Risk Linked to mtDNA Copy Number Sep 29, 2017 Shared Migraine, Heart Disease Risk Variants Emerge From GWAS Jul 25, 2017 Genetic Predisposition to High Blood Calcium Linked to Increased Heart Disease Risk Jul 17, 2017 Genetic Analysis Finds Role for Insulin Resistance, Transendothelial Migration in Heart Disease Load More Breaking News UK Biobank Study Investigates Incomplete Penetrance of Mendelian Disease Variants MDxHealth Q3 Revenues Grow 23 Percent BioMérieux Q3 Revenues Increase 11 Percent, Firm Raises 2021 Guidance Germline Cancer Risk Genes May Hold Rhabdomyosarcoma Survival Clues, Study Suggests Danaher Q3 Revenues Rise 23 Percent, Beat Wall Street Estimates Horse Genetics Study Reveals Origins of Domestication, Use in Human Culture The Scan Guidelines for Ancient DNA Work More than two dozen researchers have developed new ethical guidelines for conducting ancient DNA research, which they present in Nature. And Cleared A UK regulator has cleared former UK Prime Minister David Cameron in concerns he should have registered as a consultant-lobbyist for his work with Illumina, according to the Financial Times. Suit Over Allegations The Boston Globe reports that David Sabatini, who was placed on leave from MIT after allegations of sexual harassment, is suing his accuser, the Whitehead Institute, and the institute's director. Nature Papers on Esophageal Cancer, Origin of Modern Horses, Exome Sequencing of UK Biobank Participants In Nature this week: genetic and environmental influences of esophageal cancer, domestic horse origin traced to Western Eurasian steppes, and more.