COPD
Single-Cell Atlas of Human Lung Highlights Differences Between Healthy, Diseased States
The atlas, based on data from nearly 40 prior studies, also identified new lung cell types and should serve as a universal reference for future research.
COPD Risk Loci Uncovered With GWAS, Machine Learning-Based Phenotyping
Using a machine learning model for distinguishing individuals with or without COPD, researchers identified dozens of new and known risk loci.
Lung Function GWAS Meta-Analysis Yields Insights Into Healthy, Diseased States
A multi-ancestry meta-analysis revealed more than 550 lung function-related genes, along with genetic risk scores linked to several traits or conditions.
In a bid to expand recognition and treatment of alpha-1 antitrypsin deficiency, a cause of COPD, Grifols is making its over-the-counter genetic test available for free.
Polygenic Transcriptome Risk Scores for COPD Show Improved Cross-Ancestry Portability
Researchers found that polygenic transcriptome risk scores worked better across ethnicities than polygenic risk scores to predict chronic obstructive pulmonary disease risk.