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Colorectal Cancer

News and reporting on colorectal cancer.

The agreement formalizes a marketing partnership with GeneDiagnostics to sell the ColonSentry test in certain parts of China.

Potsdam-based Signature Dx plans to launch by the fourth quarter of this year two array-based in vitro diagnostics for colorectal cancer. The company will first launch the tests in Europe and intends to seek US regulatory approval at an unspecified time in the future.

Signature Dx will use Affy's microarray technology in two tests it is developing for colorectal cancer.

The licensing agreement marks the first time that a company other than Exiqon will use the locked nucleic acid technology to develop diagnostic products.

The agency added new pharmacogenetic information to the label of the metastatic colorectal cancer treatment irinotecan regarding heightened risk for grade 4 neutropenia in patients homozygous and heterozygous for the UGT1A1*28 allele.

Asuragen will incorporate the mutation into diagnostic test kits and use it in its clinical lab for research and patient testing.

The term sheet agreement with GeneDiagnostics would cover marketing for the ColonSentry in Shanghai, Zhejiang, and Jiangsu.

Researchers from Ghent University and the National University of Ireland have identified and validated a panel of six microRNAs ideal for use as reference genes in PCR-based miRNA expression analysis in colorectal cancer.

The non-exclusive license grants Warnex the right to establish a PCR-based laboratory-developed test for Septin9 and offer colorectal cancer blood testing services in Canada.

In the May issue of Cancer Prevention Research, Steven Lipkin and colleagues reported that in colon cancer cell lines, the protective effect against colorectal cancer was stronger in cells with a particular SNP in the HMGCR gene.

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Nature News writes that additional details about the UK plan for an agency to support high-risk, high-reward science are needed.

The New York Times reports that the US Food and Drug Administration has authorized Johnson & Johnson's SARS-CoV-2 vaccine.

The Wall Street Journal writes new studies are giving glimpses into the origins of SARS-CoV-2.

In PLOS this week: analysis of Plasmodium population structure, qPCR assay to diagnose scabies, and more.