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Colorectal Cancer

News and reporting on colorectal cancer.

The partners will assess potential biomarkers, beyond KRAS, of response to cancer drug cetuximab (Erbitux).

Synlab has started offering Epi proColon, Epigenomics' PCR-based blood test for early detection of colorectal cancer, through 55 German sites in its network. In addition, Epigenomics recently raised €33.1 million ($44.2 million) through a combined private and public share offering.

PCR Insider spoke with Mohammad Ilyas of the Queen's Medical Centre at Nottingham University about using quick-multiplex-consensus PCR followed by high-resolution melting to detect mutations in formalin-fixed, paraffin-embedded tissue.

When Vectibix received approval from the US Food and Drug Administration in 2006, "Amgen already knew the response rate was low," according to an Amgen official. The company began collecting patient tissue samples from mid-2005 to early 2007, knowing it would "need those samples for a biomarker analysis."

"DxS is seeking to avoid its exclusive obligation with Roche because it no longer finds it advantageous to benefit from the Roche distribution network," but a termination of the agreement would cause "irreparable" harm, Roche stated in a recently filed complaint.

The CDC's Muin Khoury is disappointed in the paucity of genomics-related prevention and education objectives that have been proposed as part of the US federal government's Healthy People 2020 project.

"Our data reinforce the importance of the KRAS mutation as a predictive biomarker for responsiveness to Vectibix therapy," said Roger Perlmutter, Amgen's executive vice president of research and development.

If the researchers are successful, GMU's Emanuel Petricoin believes it could lead to the development of the first ever protein activation companion assay.

New Releases: Jan 13, 2010

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Abbott/Quest/Epigenomics' Septin 9 Colorectal Cancer Test

Genomic Health will also hire additional sales people in connection with the launch, President and CEO Kim Popovits said yesterday at the JP Morgan Healthcare Conference.

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The Chan Zuckerberg Biohub is working with California's health department to sequence viral samples from COVID-19 patients to trace viral introductions, according to the San Francisco Chronicle.

Despite differences in their migration habits, eastern and western monarch butterflies are genetically similar, according to a study in Molecular Ecology.

The UK is implementing COVID-19 testing with a 90-minute turnaround time.

In PLOS this week: identification of fungal species in subcutaneous infections, sequencing of Campylobacter found in raw meat from retail stores, and more.