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Colorectal Cancer

News and reporting on colorectal cancer.

The protocol for the trial, which will study overall survival in Vectibix-treated chemorefractory patients with wild-type KRAS tumors, is currently being reviewed by the FDA.

The partners will use Aushon's technology to develop predictive diagnostic markers for liver metastases of colorectal cancer.

Diagnoplex received a boost toward commercializing its flagship PCR-based colon cancer blood test in the form of a "substantial" Series A financing extension by fellow Swiss biopharmaceutical conglomerate Debiopharm Group.

The study identified 27 genes that might impact colon cancer patients' response to oxaliplatin, a finding that could help Genomic Health add a treatment benefit indication to its Oncotype DX test.

Exact has been evaluating several MDxHealth methylation biomarkers, among other biomarkers, as well as its methylation-specific PCR technology, under a previous licensing agreement.

MDxHealth said that Exact's decision to move forward with the test has triggered a milestone payment of an undisclosed amount. The company is also entitled to royalties on sales of the test once it is commercialized.

The firm also said that Israeli insurance firm Clalit has agreed to provide reimbursement for the Oncotype Dx colon cancer test.

Veridex has received rights to use certain DNA methylation biomarkers for colorectal cancer and prostate cancer screening.

Gen-Probe's Prodesse ProAdeno+ assay; Myconostica's MycAssay Aspergillus test; Warnex launches Septin9 test in Canada.

The firms plan to develop other assays for predicting patient response in clinical studies.

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The US has sent its formal notice of withdrawal from the World Health Organization, according to the Wall Street Journal.

The Harvard Crimson reports that Harvard and MIT are suing the Department of Homeland Security and ICE over the new international student visa policy.

Science reports that a draft spending bill would increase the US National Institutes of Health budget by 13 percent.

In Nucleic Acids Research this week: algorithm to determine molecular sequence types and other microbial features, computational method to uncover R-loop structures, and more.