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Colorectal Cancer

News and reporting on colorectal cancer.

Seegene will contribute its DPO and READ PCR technologies; while SMC will provide clinical and disease pathology expertise and the first test sites for the new assays.

Myconostica announces positive study results for MycAssay Pneumocystis and MycAssay Aspergillus assays; Exiqon reports positive results for MiRcury LNA Universal RT microRNA PCR test for colorectal cancer.

The UK firm also joined the COLTHERES Consortium, tasked to define and carry out biomarker-driven clinical trials with the goal of improving cancer therapy outcomes.

New Releases: Mar 30, 2011


Everist's OncoDefender-CRC

Exact Sciences, which licensed the intellectual property behind ColoSure to LabCorp, is developing a next-generation, multi-gene test for colorectal cancer and plans to start clinical trials later this year to support a premarket approval application with the FDA.

The test, which was launched in late 2009, detects methylated DNA of the Septin-9 gene, which Quest licensed from Epigenomics. It is targeted at people 50 years of age and above who should be screened for colon cancer but resist.

The service, which features a panel of 74 potential cancer protein biomarkers, uses the company's real-time PCR-based proximity ligation assay-based immunoassay platform to detect markers in plasma volumes as small as 2 microliters.

OncoTrack, a new international consortium, will seek to generate high-quality genomic and epigenetic data from clinically well-defined colon cancer tumors and their metastases as part of its colon cancer project.

The firm plans to launch its OncoDefender-CRC assay later this month.

The device, named the Verisante Aura, uses Raman spectroscopy to measure levels of various biomarkers – including proteins, nucleic acids, and metabolites – in skin lesions. In initial clinical trials it distinguished between benign and malignant lesions with 100-percent sensitivity and 70-percent specificity.


A study of families explores how children transmit SARS-CoV-2, according to the Associated Press.

US Agricultural Research Service scientists have sequenced the genome of the Asian giant hornet.

According to the Economist, pooled testing for COVID-19 could help alleviate strains on testing labs.

In Science this week: MIT researchers outline approach dubbed translatable components regression to predict treatment response among IBD patients.