chromosomal abnormalities Arcedi Biotech Introduces NIPT Analyzing DNA From Rare Fetal Cells in Maternal Blood Premium The company is positioning the blood-based test as an alternative to invasive chorionic villus sampling, the current standard in Denmark. CRISPR-Cas9 Genome Editing Can Lead to Extensive Chromosome Rearrangements A study showed that chromothripsis, a mutational process that can lead to congenital disease and cancer, can result from on-target editing with Cas9. Prenatal Diagnosis Society Recommends cfDNA Screening for Autosomal Trisomies in Twin Pregnancies The literature shows high specificity and sensitivity for cfDNA testing in twin pregnancies. It could also be a viable screening option for triplet pregnancies. ACOG Guidelines Recommend NIPT for All Pregnancies Regardless of Risk The organization had previously only recommended the use of noninvasive prenatal testing in individuals 35 and older or with other known risk factors. Bionano Genomics Expecting Clinical Validation Studies to Drive Platform Adoption Premium The firm is hoping that researcher-generated data will soon be published in peer-reviewed papers, while it weathers the COVID-19 pandemic. Nov 8, 2019 Some Call for Expanded Payor Coverage of NIPS but Reluctance Remains Premium Aug 9, 2019 Illumina Begins Upgrading NIPT Customers to New Version of Test With Genome-Wide Options Premium Mar 29, 2019 Prenatal Testing Decision Making Tied to Women's Aversion to Risk, Ambiguity Nov 13, 2018 Angle to Enter NIPT Market With Rare Cell Isolation Platform Premium Apr 5, 2018 Singlera to Use $60M Funding to Support Launch of IVDs, Research Into Very Early Detection of Cancer Premium Mar 2, 2018 Mosaic Maternal Fragile Site Expansion Adds to List of Variants Causing False-Positive NIPT Results Oct 11, 2017 Natera Validates Panorama NIPT for Twin Pregnancies; Includes Zygosity, Fetal Sex Determination Premium Dec 21, 2016 Size-Based NIPT Approach Helps Clarify Origin of Subchromosomal Abnormalities Premium Nov 22, 2016 NIH Awards Albert Einstein Scientist $7.5M to Study Genetics of Congenital Heart Abnormalities Nov 2, 2016 Fetal Cell-Based Noninvasive Prenatal Testing Advances With Three New Feasibility Studies Premium Jun 14, 2016 CombiMatrix Believes NGS Preimplantation Genetic Screening Test Will Attract New Customers Premium Feb 26, 2016 Sequenom Publishes Clinical Validation of MaterniT Genome Test Jan 28, 2016 Study Supports Use of Sequencing in Clinical Cytogenetics, Pathogenic CNV Detection Jan 15, 2016 UK National Screening Committee Recommends NIPT Evaluation as Part of Existing Program Dec 18, 2015 India's MedGenome Begins Offering Natera's Panorama NIPT Dec 17, 2015 Researchers Say NIPT Has Limited Clinical Utility for Subchromosomal Abnormalities Nov 10, 2015 NIPT for Sub-Chromosomal Abnormalities Dependent on Fetal DNA Fraction, Sequencing Depth Premium Oct 22, 2015 Multiplicom Gets CE-IVD Mark for Clarigo NIPT Aug 18, 2015 CombiMatrix Lands NY State Approval for Prenatal Dx Array Jun 5, 2015 Q&A: Diana Bianchi on Consenting Women for NIPT in the Age of Incidental Findings Premium Load More Breaking News Enzo Biochem, CLX Health Partner to Support COVID-19 Testing for International Travel Type 1 Diabetes GWAS, Fine-Mapping Leads to New Genetic Loci, Potential Drug Targets LSU Health Sciences Center Wins $2.4M to Lead SARS-CoV-2 Variant Sequencing Program NanoString Technologies, Parker Institute for Cancer Immunotherapy Partner on Cell Therapy Project BGI Americas Collaborating With Champions Oncology on Proteomic Cancer Research Personal Genome Diagnostics Inks Cancer Genomic Profiling Deal with Duke University Health System The Scan Missed Early Cases A retrospective analysis of blood samples suggests early SARS-CoV-2 infections may have been missed in the US, the New York Times reports. Limited Journal Editor Diversity A survey finds low diversity among scientific and medical journal editors, according to The Scientist. How Much of a Threat? Science writes that need for a provision aimed at shoring up genomic data security within a new US bill is being questioned. PNAS Papers on Historic Helicobacter Spread, Brain Development, C. difficile RNAs In PNAS this week: Helicobacter genetic diversity gives insight into human migrations, gene expression patterns of brain development, and more.