cervical pre-cancer Qiagen, Inovio Expand CDx Partnership, Starting With NGS Test for Cervical Dysplasia Therapy The partners will develop a test to identify women most likely to benefit from VGX-3100, Inovio's immunotherapy to treat HPV-associated advanced cervical dysplasia. BD Receives FDA Supplemental Premarket Approval for Extended Genotyping HPV MDx The expanded test can be used for genotype risk-based patient monitoring to prevent over-treatment, BD has said. Cervicovaginal Microbiomes of HPV-Infected Women Lead To Potential Pre-Cancer Marker Profiling microbial communities in cervicovaginal samples from women carrying high-risk HPV strains, researchers found possible markers of pre-cancer progression. Transcriptome-Based HPV Assay Shows Correlation With High-Grade Cytology Premium The new test uses the number of sequencing reads at specific early and late HPV transcripts as a biomarker for high-grade cytology. Qiagen, Inovio to Develop CDx for Immunotherapy Targeting Precancerous Cervical Lesions The test will guide clinical decision making related to Inovio's DNA-based immunotherapy to treat cervical dysplasia caused by human papillomavirus. May 13, 2019 Studies Outline Outcomes Associated With Cervical Cancer Screening, Triage Strategies Feb 20, 2019 Cervical Microbes Potentially Tied to Viral Infections, High-Grade Lesions Nov 2, 2018 Negative HPV DNA Test Result Could Lessen Need for Cervical Cancer Screening Aug 21, 2018 USPSTF Cervical Cancer Screening Recommendations Strike Compromise on Cotesting Oct 6, 2017 Lab Industry Reacts to USPSTF Recommendation Against Cervical Cancer Co-testing Sep 7, 2017 Enhanced HPV16 Diversity Suspected of Protecting Against Cervical Cancer Feb 8, 2016 Hungary's Neumann Diagnostics Readies HPV, Cervical Cancer Risk Test for European Market Premium Dec 14, 2015 Genomic Vision Partners With Reims University Hospital to Develop Cervical Cancer Screening Tool Jan 14, 2015 MDxHealth Licenses Epigenetic PCR Technology to Oncgnostics Jul 19, 2011 Roche Acquiring Cervical Cancer Test Developer MTM Laboratories for up to $269M Jan 26, 2011 MTM Laboratories Planning FDA Filings for Cervical Disease Tests Jul 8, 2010 Dx Focus Jul 8, 2010: Clinical and Regulatory PCR and Nucleic Acid Testing News Premium Breaking News Top Five Articles on GenomeWeb Last Week: Guardant Health Layoffs, Ultima Genomics Use, More New Products Posted to GenomeWeb: Qiagen, Thermo Fisher, Bionano Genomics, BillionToOne, More People in the News at Illumina Ventures, Element Biosciences, Epigenomics, Exagen, More Genomic Approaches Boost Rare Disease Diagnoses in Middle Eastern Patient Population GeneDx to Raise $150M in Public and Direct Stock Offerings The Scan Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups. Genome-Wide Analysis Sheds Light on Genetics of ADHD A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder. MicroRNA Cotargeting Linked to Lupus A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus. Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.