central nervous system disorder

The transcription factor FOXM1 marked meningioma cases with poorer outcomes and enhanced cell proliferation, based on integrated exome, expression, and epigenetic profiles.

The researchers used DNA methylation profiles to define 82 central nervous system tumor classes, some of which differed from WHO tumor classes.

In conjunction with its 51 percent stake in Immuneering, Teva will have the right of first refusal in projects related to CNS disorder treatments. 

NEW YORK (GenomeWeb News) – The Icahn School of Medicine at Mt. Sinai and biopharmaceutical firm Berg today announced a five-year partnership aimed at cancer, as well as central nervous system and endocrine disorders.

NEW YORK (GenomeWeb News) – Roche today announced that it has teamed with the Innovative Medicines Initiative to lead a consortium of industry and academic partners that will use stem cells for drug discovery research.

By a GenomeWeb staff reporter
NEW YORK (GenomeWeb News) – UK-based NextGen Group announced this week it has completed the formation of a diagnostics subsidiary to develop tests for central nervous system disorders.

Using its DiscoveryMAP protein biomarker discovery platform, the company identified a biomarker pattern useful in monitoring disease progression and predicting and monitoring the efficacy of a compound in Roche's CNS pipeline.

The firms will offer clients access to their complementary drug discovery platforms for identifying and developing new therapeutics for CNS disorders.

The companies will co-develop seven assays for pathogens associated with respiratory, enteric, and central nervous system diseases.

The work identified 1,461 proteins tied to more than130 brain diseases, suggesting that synaptic proteins may figure more prominently in nervous system disorders than previously thought and could represent promising new targets for drug development.

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An Australian-led team has generated a draft genome assembly of the invasive cane toad in hopes it will help in population control, the Sydney Morning Herald reports.

The New York Times reports that the US Department of Defense has implemented about half the recommendations made to improve safe handling of dangerous agents.

In PLOS this week: approach for teasing out archaic introgression in human genomes, immune transcription features in HCV infection, and more.

Stat News reports that Maryland is promoting itself to the biotech industry with a mobile billboard.