central nervous system disorder Expression-Based Survival Signature Proposed for Glioblastoma Using RNA sequence data from the Cancer Genome Atlas and the Chinese Glioma Genome Atlas, researchers identified six genes with expression ties to overall survival. MicroRNAs Provide Prognostic Clues in Primary Central Nervous System Lymphoma An array-based analysis involving more than two dozen patients led to a miRNA signature associated with overall survival in primary central nervous system lymphoma. Aggressive Meningioma Linked to Transcription Factor Activity The transcription factor FOXM1 marked meningioma cases with poorer outcomes and enhanced cell proliferation, based on integrated exome, expression, and epigenetic profiles. DNA Methylation Data Helps Refine Classification of Central Nervous System Tumors The researchers used DNA methylation profiles to define 82 central nervous system tumor classes, some of which differed from WHO tumor classes. Generic Drug Manufacturer Teva Takes Majority Stake in Genomic Analysis Shop Immuneering In conjunction with its 51 percent stake in Immuneering, Teva will have the right of first refusal in projects related to CNS disorder treatments. Oct 10, 2013 Mt. Sinai, Berg Ink Omics Deal Directed at Cancer, CNS, Endocrine Disorders Dec 5, 2012 Roche, IMI Lead Stem Cell Research Effort Feb 24, 2012 NextGen Creates Diagnostics Subsidiary for CNS Test Development May 27, 2011 RBM Achieves Milestone in Companion Diagnostic Project with Roche Premium May 25, 2011 Evotec, PsychoGenics Partner on CNS Drug Discovery Services May 9, 2011 BD Diagnostics, Diagenode to Co-develop Assays on BD Max System Dec 24, 2010 Sanger, Edinburgh Scientists Complete First Proteomic Analysis of Human Postsynaptic Density Premium Nov 12, 2010 Takeda, Sage Bionetworks Partner to Find Drug Targets for CNS Breaking News Cytosine Base Editor Enables Genome-Wide Genetic Function Screening G42 Healthcare, Seegene to Offer Mobile Molecular Diagnostic Labs in Middle East, North Africa JP Morgan, Cowen Initiate Coverage of Singular Genomics Systems Top Five Articles on GenomeWeb Last Week: Danaher, Becton Dickinson, 23andMe, and More Berry Oncology, Alibaba Health Partner to Offer Early Cancer Screening, Health Services Roche Receives FDA EUA for PCR-Based, Point-of-Care SARS-CoV-2 Test The Scan Renewed Gain-of-Function Worries The New York Times writes that the pandemic is renewing concerns about gain-of-function research. Who's Getting the Patents? A trio of researchers has analyzed gender trends in biomedical patents issued between 1976 and 2010 in the US, New Scientist reports. Other Uses CBS Sunday Morning looks at how mRNA vaccine technology could be applied beyond SARS-CoV-2. PLOS Papers Present Analysis of Cervicovaginal Microbiome, Glycosylation in Model Archaea, More In PLOS this week: functional potential of the cervicovaginal microbiome, glycosylation patterns in model archaea, and more.