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celiac disease

The immune sequencing firm has engaged the FDA in discussions over how to get regulatory approval for one test for several seemingly different diseases.

The award will go to Jocelyn Silvester of Children's Hospital Boston, to fund transcriptomics research on intestinal inflammation caused by gluten.

The immune sequencing firm is working on kit-ifying its two existing tests, as well as developing a second clinical test and expanding the label for clonoSeq.

Researchers documented genetic associations, trait heritability, and more with data from GWAS on 778 binary or non-binary traits in UK Biobank participants.

Gluten Removal

Researchers used gene editing to remove most of the gluten from bread and durum wheat lines, New Scientist reports.

In Science this week: updated gorilla genome, long non-coding RNA linked to celiac disease, and more.

Researchers identified a common variant in a long non-coding RNA that may contribute to inflammation seen in patients diagnosed with celiac disease. 

Using genotyping data, the Children's Hospital of Philadelphia-led team found high heritability across pediatric-onset autoimmune diseases.

Through a meta-analysis of 10 pediatric-onset autoimmune diseases, Children's Hospital of Philadelphia researchers found 22 loci shared among the conditions.

According to one of the researchers, the study offers basic scientific insights into celiac disease and could prove useful in developing therapies for the disease.

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The Washington Post reports that Herbert Tabor, who worked at the US National Institutes of Health for 77 years, has died at 101.

The World Bank is seeking approval for a $12 billion plan to provide low-income nations with funds to procure SARS-CoV-2 vaccines, according to Reuters.

Science writes that public health officials and others are debating whether cycle threshold values should be included on SARS-CoV-2 results.

In Nucleic Acids Research this week: online database of SARS-CoV-2 protein structures, atlas of the human brain, and more.