cardiomyopathy

Retraction Watch reports that Nature has added an editor's note to a paper describing the correction of a pathogenic mutation in human embryos.

In Genome Biology this week: computational approach for analyzing noisy single-cell sequencing profiles, eQTLs of dilated cardiomyopathy, and more.

Testing for Relief

Minneapolis-St. Paul's KARE tells the story of a woman who'd thought she'd dodged genetic hypertrophic cardiomyopathy and sought testing for her children.

Investigators compared RNA sequence data in heart samples from individuals with dilated cardiomyopathy and samples from healthy transplant donor hearts.

An exome-wide association study involving almost 2,800 individuals with dilated cardiomyopathy led to six new and two known susceptibility loci.

After six months of follow up, the costs of additional tests and consultations in the group receiving whole-genome sequencing were not significantly higher than in the control group.

Harvard researchers found that variants previously classified as pathogenic were in fact benign, disproportionately affecting patients of African ancestry. 

Last week, the firm launched AtheroGxOne the second of two cardiovascular next-gen sequencing panels, and hopes to launch its first liquid biopsy test in 2017.

A significant proportion of women with peripartum cardiomyopathy had truncating mutations in genes previously implicated in dilated cardiomyopathy.

The company's platform offers space and computational tools for exploring, sharing, and storing genomic data in the context of genetic disorders.

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In a survey, about half of Canadian government scientists say they still feel as though they cannot speak freely, ScienceInsider reports.

Clinicians in China are moving ahead with a number of CRISPR trials, NPR reports, as the US embarks on its first.

The Atlantic reports that biohacker Josiah Zayner regrets injecting himself with the CRISPR gene-editing tool on stage.

In Nature this week: genomic approaches applied to study Neolithic and Bronze Age Europeans, and more.