carcinoma Cervical Cancer Exomes Point to Potentially Targetable HER, PIK3CA Pathway Changes Exome sequences from dozens of cervical cancer tumor or primary cell line samples revealed recurrent alterations affecting ERBB2/HER2 and PIK3CA pathways. Carcinoma of Unknown Primary Investigators Pursue Molecular Targets to Tailor Treatments Premium A Phase II trial is pursuing molecularly targeted treatments for CUP as a different Phase III trial failed to find benefit for expression-based primary site therapies. Stanford Team Employs 10x Genomics Platform to Find True Source of Cancer-Fighting T Cells Premium Using 10x Genomics' immune profiling and ATAC-seq assays, the researchers upended the notion that cancer-fighting T cells come from within a tumor. Checkpoint Immunotherapy Response Described in Tumors with Gene Fusion-Based Neoantigens Starting with a head and neck cancer patient who showed an impressive response to pembrolizumab, researchers profiled gene fusion neoantigens in several tumor types. Genomic Differences in Pre-Invasive Lung Cancer Lesions May Predict Outcome Researchers traced genomic, epigenomic, and expression features in lung carcinoma in situ cases that regressed or progressed to invasive lung squamous cell carcinomas. May 17, 2018 Several Cancer Types Significantly Tied to Polygenic Risk Scores in New PheWAS Nov 30, 2017 Head and Neck Cancer Characteristics, Subtypes Refined With Single-Cell Transcriptomes Jun 24, 2015 Team Reveals Feasibility of Using DNA in Blood, Saliva to Track Head, Neck Cancers Jun 18, 2015 Researchers Characterize Mutational Landscape of Serous Tubal Intraepithelial Carcinomas Mar 26, 2009 Launch Pad for Rising Stars Premium Mar 10, 2009 Funding Update for Mar 10, 2009 Premium Feb 25, 2009 UK Startup DNA Electronics Developing Handheld Device to Detect Genetic Risk for Drug AEs Premium Breaking News Cancer Prognoses Informed by Module-Based Approach, Study Finds People in the News at Illumina, Centogene, BioSkryb New Products Posted to GenomeWeb: Bio-Rad, BD, Analytik Jena, BioMérieux Genetic Technologies to Raise A$5M in Direct Stock Offering In Brief This Week: SD Biosensors, Meridian, Oncocyte, Opko Health, GeneDx, More The Scan Study Reveals New Details About Genetics of Major Cause of Female Infertility Researchers in Nature Medicine conducted a whole-exome sequencing study of mote than a thousand patients with premature ovarian insufficiency. Circulating Tumor DNA Shows Potential as Biomarker in Rare Childhood Cancer A study in the Journal of Clinical Oncology has found that circulating tumor DNA levels in rhabdomyosarcoma may serve as a biomarker for prognosis. Study Recommends Cancer Screening for Dogs Beginning Age Seven, Depending on Breed PetDx researchers report in PLOS One that annual cancer screening for dogs should begin by age seven. White-Tailed Deer Harbor SARS-CoV-2 Variants No Longer Infecting Humans, Study Finds A new study in PNAS has found that white-tailed deer could act as a reservoir of SARS-CoV-2 variants no longer found among humans.