cancer of unknown primary Canhelp Genomics Secures NMPA Approval for Pan-Cancer Tissue-Origin Assay, Analysis Software The Canhelp-Origin Test measures the gene expression pattern of 90 specific markers of tissue samples and classifies 21 major tumor types. Cancer Dx Firm C2i Genomics Raises $100M in Financing The company will use the funds to accelerate the clinical development and commercialization of its minimal residual disease detection C2-Intelligence Platform. CRISPR-Cas9 Genome Editing Can Lead to Extensive Chromosome Rearrangements A study showed that chromothripsis, a mutational process that can lead to congenital disease and cancer, can result from on-target editing with Cas9. Caris Shares Data for AI-Driven Tumor Origin Prediction, Hinting at Diagnostic, Patient Benefit Premium Investigators reported that the classifier could correctly predict cancer type with over 94 percent accuracy and highlighted impacts in a commercially tested cohort. GenomeWeb Index Gains 49 Percent in 2020, Outperforming Wider Markets Despite the havoc wreaked by the COVID-19 pandemic on the economy, several companies in the index saw their shares rise by triple-digit percentages last year. Dec 28, 2020 M&A Deals in MDx/Omics Research Tools Space Fall 13 Percent in 2020 Premium Dec 17, 2020 New Rhesus Macaque Reference Genome Holds Potential for Human Disease, Evolution Research Dec 2, 2020 Epigenome Study Maps Hydroxymethylation Across Diverse Human Tissue Types Nov 23, 2020 Broad Institute DepMap Project Could Lead to Development of New Cancer Drugs Premium Nov 17, 2020 Diagnostics Firms, Lab Providers Form Genomic Profiling Coalition Oct 16, 2020 NGS-Based Profiling May Guide Treatment for Patients With Cancers of Unknown Primary Oct 13, 2020 Twist Bioscience, Neogene Therapeutics Partner to Develop Personalized CAR T Cells, TCR Therapies Sep 3, 2020 Oncocyte, Guardian Research Network Partner to Improve Precision Medicine Clinical Trials Aug 6, 2020 Personalis Q2 Revenues Up 23 Percent Jul 8, 2020 Twist Bioscience, Takeda Pharma Partner to Develop Antibodies for Oncology, Rare Diseases Jul 7, 2020 Cancer Research UK, Abcam Partner to Develop Custom Antibodies for Cancer Research Jun 23, 2020 Advanced CRISPR Screens Uncover Possible Novel Targets for Cancer Therapies Premium Jun 2, 2020 Evidence for Targeted Treatment Builds in Cancers of Unknown Primary but Randomized Data Pending Premium May 7, 2020 Personalis Q1 Revenues Up 36 Percent Apr 28, 2020 New Iteration of AACR's Project GENIE Focuses on Real-World Outcomes to Enhance Precision Oncology Premium Apr 16, 2020 Single Error in Cell Division Can Generate Great Complexity in Cancer Genomes Mar 25, 2020 Personalis Q4 Revenues Grow 38 Percent, Full-Year Revenues Up 73 Percent Mar 11, 2020 Microbiome-Based Cancer Dx Emerges From Cancer Genome Atlas Reanalysis Feb 19, 2020 Cancer, Pathology Organizations Developing Clinical Guidelines for MMR, MSI Testing Jan 27, 2020 Johns Hopkins University Opens New Cancer Center With $5M in Mark Foundation Funding Load More Breaking News SARS-CoV-2 Variants of Concerns Evolved to Modify Host Immune Response, Multiomics Study Shows People in the News at GA4GH, Mercy BioAnalytics, Deepcell, One Biosciences New Products Posted to GenomeWeb: Clinical Microbiomics, Integra Biosciences, DNAstack, Bruker Angolan Namib Desert Population Analysis Uncovers New Ancestry Group With Deep Divergence Cedars-Sinai Sets Up $25M Single Cell Precision Medicine Center The Scan Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants. Small Study of Gene Editing to Treat Sickle Cell Disease In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms. Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema. Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.