brain disease
Brain Vasculature Cell Features Spelled Out in Single-Cell Sequencing Atlas
Researchers relied on single-cell RNA sequencing to characterize vascular cell types and molecular markers found in the human brain in different developmental and disease states.
Measles Virus Mutations Found to Drive Rare Lethal Brain Infection
Researchers turned to deep genome sequencing on brain autopsy samples to understand measles virus features involved in a rare, usually deadly form of encephalitis.
Focal Epilepsy Study Uncovers Distinct Mechanism for Brain Mosaicism
Researchers found that a subset of infant focal epilepsy cases involved brain-specific mosaic mutations due to meiotic errors that were rescued in other tissues.
Brain Cell Features Detailed in Human Cell Atlas Research Collection
Research teams relied on genomic strategies to explore everything from brain cell complexity and diversity to development and gene regulation in humans and other primates.
Protein Biomarker Shows Promise for Early Detection of Parkinsonian Disorders
Using a multiplex immunoassay, investigators identified elevated levels of the enzyme DOPA decarboxylase in patients with Parkinsonian disorders.