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brain disease

From single-cell RNA sequence data on neurogenic brain samples from young and old mice, researchers saw T cell activity that seems to staunch neural stem cell proliferation.

In a set of new studies, members of an international team mapped gene variation, expression, and regulatory interactions in developing and adult human brains.

The RNA-seq data, for nearly 40,000 cells from the developing mouse brain, can be explored through an interactive online interface called Cell Seek.

Using omics and other data, researchers performed  network analyses that pointed to interactions between human herpesviruses and other Alzheimer's disease risk factors.

In an against-all-odds twist, a researcher studying exceeding rare FOXG1 mutations discovers her daughter has the syndrome.

Researchers identified somatic KRAS mutations in affected tissue from more than 60 percent of people with sporadic arteriovenous malformations of the brain.

A pair of papers has linked mutations in the DCC gene to agenesis of the corpus callosum as well as to a new syndrome.

A study of twins, unrelated individuals, and post-mortem brain samples suggests genetic factors contribute to cortical features and functions in humans.

Using a modified single-nuclei RNA sequencing pipeline adapted to deal with postmortem tissue, researchers have uncovered 16 neuronal subtypes.

NEW YORK (GenomeWeb News) – Agilent Technologies and South Korea's Daegu Gyeongbuk Institute of Science and Technology (DGIST) today announced a collaboration focused on neurometabolomics research.

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The US Food and Drug Administration is to announce stricter standards for emergency authorizations of SARS-CoV-2 vaccines, reports the Washington Post.

The Associated Press reports Johnson & Johnson is starting a late-stage clinical trial of its candidate SARS-CoV-2 vaccine.

Bloomberg reports the budget of Operation Warp Speed is actually $18 billion, higher than the number typically cited.

In Genome Research this week: genomic analysis reveals role of super-spreaders in SARS-CoV-2, epigenetic drivers of cancer, and more.