Brain Cancer News and reporting on brain cancer. Biocept Licenses CNSide Liquid Biopsy Assay to Plus Therapeutics Under the agreement, Plus is using the cerebrospinal fluid cell-based assay in its ongoing clinical trial of the radiotherapeutic rhenium 186 obisbemeda. Microenvironments Give Clues to Distinct Immunotherapy Responses in Brain Metastases, Glioblastomas Investigators found microenvironment differences in checkpoint blockade immunotherapy-treated cases involving brain metastases versus recurrent glioblastoma. New Mutations Identified in Common Childhood Brain Cancers Could Guide Personalized Treatments In a study published in PNAS, Swedish researchers identified new mutations implicated in common pediatric cancers in the noncoding regions. Biocept Prices $5M Public Offering The San Diego-based company plans to use the proceeds to advance its cerebral spinal fluid liquid biopsy assay, as well as to boost its working capital. CHLA Low-Pass WGS Liquid Biopsy Assay Could Aid Pediatric Cancer Diagnosis, Prognosis Premium The liquid biopsy assay uses low-pass whole-genome sequencing to screen for copy number alterations in blood, cerebral spinal fluid, and aqueous humor samples. Jan 18, 2023 Brain Metastases Analysis Points to Distinct Tumor Immune Microenvironments, Potential Treatments Dec 21, 2022 Glioblastoma With Wild-Type TP53 Linked to Potentially Targetable Epigenetic Alteration Dec 14, 2022 Functional Precision Medicine Firm Kiyatec Raises $18M in Series C Funding Round Oct 7, 2022 Team Untangles Mechanism Behind Noncoding Glioma Risk Variant Sep 21, 2022 Medulloblastoma Molecular Studies Point to Cell Origins, Progenitor Differentiation Jul 12, 2022 NCCN Publishes First Guidelines for Pediatric Brain Cancer, Recommends Broad NGS Profiling Jul 6, 2022 Structural Variant Study Points to Pediatric Glioma Drivers, Prognostic Features May 2, 2022 Brain Cancer Canada Funds Development of New Dx Sequencing Assay at St. Michael's Hospital Mar 21, 2022 NIH Launches New Childhood Cancer Genomics Program Nov 12, 2021 Childhood Brain Tumors in Crosshairs of New CHOP-led Sequencing Biobank Effort Premium Mar 31, 2021 Biocept Prepares for First FDA Foray With CSF Liquid Biopsy Brain Metastases Assay Premium Mar 10, 2021 Datar Cancer Genetics Obtains CE Mark for Liquid Biopsy Cancer Test Feb 11, 2021 Glioblastoma Omics Study Highlights Informative Tumor Features, Immune Subtypes Jan 11, 2021 Glioblastoma Transcriptomes Point to Mitochondrial Subtype, Potential Treatment Strategies Nov 13, 2020 Biocept Eyes Neuro-Oncology for Future Liquid Biopsy Growth as Testing Lags Amid COVID Pandemic Premium Aug 28, 2020 Tumor Immune Microenvironment Profiling Could Guide Therapy in Pediatric Brain Cancer Aug 11, 2020 Childhood Ependymoma Single-Cell Sequencing Study Reveals New Cellular Subpopulations Jul 14, 2020 Glioblastoma Brain Tumor Treatment Strategies Stem From Pharmacogenomic Analysis Jun 26, 2020 Brain, Kidney Cancer Studies Lay Path for Clinical Application of Epigenetic Liquid Biopsy Method Premium Jun 9, 2020 Glioblastoma Genomes Point to Non-Coding Driver Mutations Load More Breaking News Rare Kidney Cancer Genomic Analysis Reveals Potential Target, Suggests Treatment SEC Concludes CareDx Investigation, Recommends No Enforcement Action Streck Quality Controls for DiaSorin's Luminex Sepsis Tests Receive FDA Clearance Adela Closes $48M Financing to Develop Cancer Monitoring, Early Detection Test 3EO Health At-Home Molecular COVID-19 Test Nabs FDA EUA The Scan Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants. Small Study of Gene Editing to Treat Sickle Cell Disease In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms. Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema. Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.