blood clots

The research team found three novel polymorphisms on chromosome 20 associated with an increased risk of blood clots in populations of African descent.

Data from a dozen GWAS led researchers to venous thromboembolism-associated variants in the TSPAN15 and SLC44A2 genes.

Nanosphere said that it believes the deficiencies cited in the letter from the FDA are resolvable, and it believes that the test will ultimately gain clearance from the agency.

Rheonix plans to seek 510(k) clearance of the test from the FDA in the fourth quarter.

Findings in a NEJM study this week challenged previously reported data that alleles in the CYP2C19 gene can limit how certain carriers of the polymorphisms respond to Plavix.

While gene therapies may have high price tags, they could be cheaper than the cost of managing disease, according to MIT's Technology Review.

Researchers are looking for markers that indicate which cancer patients may respond to immunotherapies, the Associated Press writes.

In Nature this week: paternal age associated with de novo mutations in children, and more.

Nature News writes that researchers are still wrangling over the role of the p-value.