bipolar disorder Bipolar Disorder GWAS Meta-Analysis Points to Potential Treatment Targets Researchers identified 64 risk loci in a genome-wide association study meta-analysis that included almost 42,000 individuals with bipolar disorder. Case-Case GWAS Approach Identifies Loci That Differ in Frequency Across Psychiatric Disorders The approach provides new insights into genetic differences between various disorders in order to improve their diagnosis and treatment. Psychiatric Disorder Risk Affected by Dysregulation of RNA-Binding Proteins Using a deep learning approach to study mutations in target sites of RNA-binding proteins, researchers identified DDHD2 as a candidate schizophrenia risk gene. Schizophrenia Exome Studies Delineate Role of De Novo Mutations While de novo mutations appeared to make relatively modest contributions to schizophrenia risk, they recurrently affected evolutionarily conserved genes. Psychiatric Disorders, Body Mass Index Share Genetic Loci, Study Finds Some of these shared loci were associated with higher BMI, but some were linked to lower BMI, particularly those also linked to schizophrenia. Jan 7, 2020 Anxiety GWAS On Million Veteran Program Data Uncovers New Loci Dec 12, 2019 Psychiatric Disorders Fall Into Groups With Shared Genetic Contributors in GWAS Meta-Analysis Sep 25, 2019 Genetic Links Between Psychotic Experiences, Neuropsychiatric Diseases Uncovered in Study May 3, 2019 Differential Methylation of Enhancer May Lead to Abnormal Dopamine Levels in Major Psychosis May 1, 2019 Bipolar Disorder Risk Loci Reported From Psychiatric Genomics Consortium GWAS Jan 30, 2019 Polygenic Risk Scores for Three Psychiatric Disorders Linked to Depression Diagnoses Dec 13, 2018 PsychENCODE Studies Explore Brain Development, Neuropsychiatric Regulatory Features Jun 21, 2018 Large Study Uncovers Genetic Connections Between Numerous Psychiatric Disorders Jun 14, 2018 Bipolar, Schizophrenia GWAS Leads to Shared, Distinct Risk Variants May 31, 2018 Rare Truncating Mutations Play Role in Neurodevelopmental Disease May 18, 2018 Initial Data Bolsters Laguna Diagnostics' Plans for mRNA Psychiatric Diagnostic Premium May 15, 2018 American Gut Project Reports Microbiome Results for 11K Participants Feb 8, 2018 Brain Transcriptome Distinctions, Overlaps Characterized in Neuropsychiatric Conditions Nov 9, 2017 Lithium Response in Bipolar Disorder Linked to Schizophrenia-Related Variants Aug 14, 2017 GWAS Data Analysis Generates List of Candidate Drugs for Psychiatric Conditions Aug 2, 2017 23andMe, Lundbeck, Milken Institute Partner on Depressive, Bipolar Disorders Study Jun 19, 2017 Psychosis-Associated Mutations IDed in Brain-Expressed Gene Mar 3, 2017 Psychiatric Disorder Sequencing Project Adds 10x Genomics Tech for Phasing, Structural Variant ID Premium Dec 5, 2016 Six Loci Linked to Personality Traits in Meta-Analysis Jan 27, 2016 Researchers Uncover 17 Novel Genes Related to Developmental Brain Disorders Load More Breaking News Enzo Biochem, CLX Health Partner to Support COVID-19 Testing for International Travel Type 1 Diabetes GWAS, Fine-Mapping Leads to New Genetic Loci, Potential Drug Targets LSU Health Sciences Center Wins $2.4M to Lead SARS-CoV-2 Variant Sequencing Program NanoString Technologies, Parker Institute for Cancer Immunotherapy Partner on Cell Therapy Project BGI Americas Collaborating With Champions Oncology on Proteomic Cancer Research Personal Genome Diagnostics Inks Cancer Genomic Profiling Deal with Duke University Health System The Scan Missed Early Cases A retrospective analysis of blood samples suggests early SARS-CoV-2 infections may have been missed in the US, the New York Times reports. Limited Journal Editor Diversity A survey finds low diversity among scientific and medical journal editors, according to The Scientist. How Much of a Threat? Science writes that need for a provision aimed at shoring up genomic data security within a new US bill is being questioned. PNAS Papers on Historic Helicobacter Spread, Brain Development, C. difficile RNAs In PNAS this week: Helicobacter genetic diversity gives insight into human migrations, gene expression patterns of brain development, and more.