bipolar disorder New Approach Identifies Candidate Causal Variants for Neuropsychiatric, Neurodevelopmental Conditions Combining eQTL and GWAS results, researchers at the Icahn School of Medicine at Mount Sinai detected hundreds of candidate causal variants for various brain traits. Analysis Estimates Psychiatric Disorder Risk from Specific Copy Number Variants in Danish Cohort The population-based analysis found that deletions and duplications in six genomic loci generally increased risk for autism spectrum disorder and ADHD. Bipolar Disorder GWAS Meta-Analysis Points to Potential Treatment Targets Researchers identified 64 risk loci in a genome-wide association study meta-analysis that included almost 42,000 individuals with bipolar disorder. Case-Case GWAS Approach Identifies Loci That Differ in Frequency Across Psychiatric Disorders The approach provides new insights into genetic differences between various disorders in order to improve their diagnosis and treatment. Psychiatric Disorder Risk Affected by Dysregulation of RNA-Binding Proteins Using a deep learning approach to study mutations in target sites of RNA-binding proteins, researchers identified DDHD2 as a candidate schizophrenia risk gene. Jan 14, 2020 Schizophrenia Exome Studies Delineate Role of De Novo Mutations Jan 8, 2020 Psychiatric Disorders, Body Mass Index Share Genetic Loci, Study Finds Jan 7, 2020 Anxiety GWAS On Million Veteran Program Data Uncovers New Loci Dec 12, 2019 Psychiatric Disorders Fall Into Groups With Shared Genetic Contributors in GWAS Meta-Analysis Sep 25, 2019 Genetic Links Between Psychotic Experiences, Neuropsychiatric Diseases Uncovered in Study May 3, 2019 Differential Methylation of Enhancer May Lead to Abnormal Dopamine Levels in Major Psychosis May 1, 2019 Bipolar Disorder Risk Loci Reported From Psychiatric Genomics Consortium GWAS Jan 30, 2019 Polygenic Risk Scores for Three Psychiatric Disorders Linked to Depression Diagnoses Dec 13, 2018 PsychENCODE Studies Explore Brain Development, Neuropsychiatric Regulatory Features Jun 21, 2018 Large Study Uncovers Genetic Connections Between Numerous Psychiatric Disorders Jun 14, 2018 Bipolar, Schizophrenia GWAS Leads to Shared, Distinct Risk Variants May 31, 2018 Rare Truncating Mutations Play Role in Neurodevelopmental Disease May 18, 2018 Initial Data Bolsters Laguna Diagnostics' Plans for mRNA Psychiatric Diagnostic Premium May 15, 2018 American Gut Project Reports Microbiome Results for 11K Participants Feb 8, 2018 Brain Transcriptome Distinctions, Overlaps Characterized in Neuropsychiatric Conditions Nov 9, 2017 Lithium Response in Bipolar Disorder Linked to Schizophrenia-Related Variants Aug 14, 2017 GWAS Data Analysis Generates List of Candidate Drugs for Psychiatric Conditions Aug 2, 2017 23andMe, Lundbeck, Milken Institute Partner on Depressive, Bipolar Disorders Study Jun 19, 2017 Psychosis-Associated Mutations IDed in Brain-Expressed Gene Mar 3, 2017 Psychiatric Disorder Sequencing Project Adds 10x Genomics Tech for Phasing, Structural Variant ID Premium Load More Breaking News New Approach Identifies Candidate Causal Variants for Neuropsychiatric, Neurodevelopmental Conditions People in the News: Baylor's Thomas Caskey Dies; New Appointments at UK Biobank, CS Genetics, More In Brief This Week: Pathogenomix, Uniogen, Genetic Technologies, DnaNudge, Gravity Diagnostics, More New Products Posted to GenomeWeb: Biodesix, Curio Genomics, Akoya Biosciences, More NIH Earmarks $170M for All of Us Program's Personalized Nutrition Study Taiwanese Firm's IP Asserted in Suit Against Pacific Biosciences Found Partially Unpatentable The Scan Omicron's Sewage Path The New York Times writes that testing sewage is helping public health officials track Omicron. IBM Sells Part of Watson Health The Wall Street Journal reports IBM is selling part of its Watson Health business to an investment firm. Identifying the Right Whales The Boston Globe writes that genetic testing has helped identify North American right whales and find that weaning can take place earlier than thought. Science Papers on Approach to Quickly Sort Single Cells, Alternative Splicing in Cancer In Science this week: high-speed sorting of single cells using fluorescence imaging, and more.