bipolar disorder
Bipolar Disorder GWAS Meta-Analysis Points to Potential Treatment Targets
Researchers identified 64 risk loci in a genome-wide association study meta-analysis that included almost 42,000 individuals with bipolar disorder.
Case-Case GWAS Approach Identifies Loci That Differ in Frequency Across Psychiatric Disorders
The approach provides new insights into genetic differences between various disorders in order to improve their diagnosis and treatment.
Psychiatric Disorder Risk Affected by Dysregulation of RNA-Binding Proteins
Using a deep learning approach to study mutations in target sites of RNA-binding proteins, researchers identified DDHD2 as a candidate schizophrenia risk gene.
Schizophrenia Exome Studies Delineate Role of De Novo Mutations
While de novo mutations appeared to make relatively modest contributions to schizophrenia risk, they recurrently affected evolutionarily conserved genes.
Psychiatric Disorders, Body Mass Index Share Genetic Loci, Study Finds
Some of these shared loci were associated with higher BMI, but some were linked to lower BMI, particularly those also linked to schizophrenia.
May 18, 2018