bipolar disorder

A genome-wide association study meta-analysis found bipolar disorder patients with poor response to lithium have more polygenic risk factors for schizophrenia.

This Week in PNAS

In PNAS this week: links between the gut microbiome and multiple sclerosis, and more.

Researchers from Hong Kong imputed transcriptomes from GWAS data and compared them to drug-induced gene expression profiles.

The study will combine cognitive assessments with genetic data and survey responses to gain insights into the causes of these two mental health conditions.

This Week in Nature

In Nature this week: fetal variants influence maternal risk of preeclampsia, and more.

Researchers identified truncating, psychosis-related mutations in RBM12 in a family affected by schizophrenia or other psychosis disorders.

Researchers for the InPSYght project are sequencing 10,000 genomes and generating linked-read data for 500 to better understand schizophrenia and bipolar disorder. 

The international team of researchers also examined the genetic ties between personality traits and psychiatric disorders.

The Geisinger Health System team found 241 genes, including 17 new ones, which could be related to autism, schizophrenia, and other disorders.

Using Myriad RBM's platform, Mayo researchers identify proteins that could be markers of bipolar I depression.

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Rare gene mutations are guiding the search for drugs to manage chronic pain without opioids, according to CNBC.

The new Francis Crick Institute building can get too noisy for some researchers to concentrate, according to the Guardian.

CBS News reports that there are still many vacancies at the White House Office of Science and Technology Policy, but that it's uncertain whether they will be filled.

In Nucleic Acids Research this week: pipeline to analyze and visualize bacterial genomes, database of global set of human genomes, and more.