bipolar disorder
New Approach Identifies Candidate Causal Variants for Neuropsychiatric, Neurodevelopmental Conditions
Combining eQTL and GWAS results, researchers at the Icahn School of Medicine at Mount Sinai detected hundreds of candidate causal variants for various brain traits.
Analysis Estimates Psychiatric Disorder Risk from Specific Copy Number Variants in Danish Cohort
The population-based analysis found that deletions and duplications in six genomic loci generally increased risk for autism spectrum disorder and ADHD.
Bipolar Disorder GWAS Meta-Analysis Points to Potential Treatment Targets
Researchers identified 64 risk loci in a genome-wide association study meta-analysis that included almost 42,000 individuals with bipolar disorder.
Case-Case GWAS Approach Identifies Loci That Differ in Frequency Across Psychiatric Disorders
The approach provides new insights into genetic differences between various disorders in order to improve their diagnosis and treatment.
Psychiatric Disorder Risk Affected by Dysregulation of RNA-Binding Proteins
Using a deep learning approach to study mutations in target sites of RNA-binding proteins, researchers identified DDHD2 as a candidate schizophrenia risk gene.