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Study Links Maternal Mental Illness-Related Variants to Perinatal Risk Factors For Offspring

Researchers identified relationships between pregnancy-related maternal traits and behaviors and polygenic risk scores for half a dozen mental health conditions.

Polygenic Risk Scores for Neuropsychiatric Conditions in Civilians Are Generalizable to Veterans

Data from the US Million Veteran Program indicates that schizophrenia PRS developed with civilian data can identify veterans at risk of the condition despite differences between the cohorts.

NYGC Psychiatric Disease Database Project Aims to Kickstart Precision Medicine for Mental Illness
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The center is leading a group that hopes to generate whole-genome sequencing data for psychiatric patients from a large, existing New York state clinical database.

Schizophrenia, Bipolar Disorder Risk Traced to Common, Rare Variants in New Genetic Studies

Researchers found that rare and common genetic risk factors for schizophrenia discovered in the two studies converged on many of the same biological mechanisms.

Leadership Roles Linked to Increased Bipolar Disorder Risk in New GWAS

The study uncovered genetic ties between holding a leadership position and intelligence, but also with mental health-related traits.

Mar 8, 2022

Bipolar Disorder Study Finds Role for Gene Expression Changes Affecting Nerve Synapses 

Jan 21, 2022

New Approach Identifies Candidate Causal Variants for Neuropsychiatric, Neurodevelopmental Conditions

Nov 24, 2021

Analysis Estimates Psychiatric Disorder Risk from Specific Copy Number Variants in Danish Cohort

May 17, 2021

Bipolar Disorder GWAS Meta-Analysis Points to Potential Treatment Targets

Mar 8, 2021

Case-Case GWAS Approach Identifies Loci That Differ in Frequency Across Psychiatric Disorders

Jan 19, 2021

Psychiatric Disorder Risk Affected by Dysregulation of RNA-Binding Proteins

Jan 14, 2020

Schizophrenia Exome Studies Delineate Role of De Novo Mutations

Jan 8, 2020

Psychiatric Disorders, Body Mass Index Share Genetic Loci, Study Finds

Jan 7, 2020

Anxiety GWAS On Million Veteran Program Data Uncovers New Loci

Dec 12, 2019

Psychiatric Disorders Fall Into Groups With Shared Genetic Contributors in GWAS Meta-Analysis

Sep 25, 2019

Genetic Links Between Psychotic Experiences, Neuropsychiatric Diseases Uncovered in Study

May 3, 2019

Differential Methylation of Enhancer May Lead to Abnormal Dopamine Levels in Major Psychosis

May 1, 2019

Bipolar Disorder Risk Loci Reported From Psychiatric Genomics Consortium GWAS

Jan 30, 2019

Polygenic Risk Scores for Three Psychiatric Disorders Linked to Depression Diagnoses

Dec 13, 2018

PsychENCODE Studies Explore Brain Development, Neuropsychiatric Regulatory Features

Jun 21, 2018

Large Study Uncovers Genetic Connections Between Numerous Psychiatric Disorders

Jun 14, 2018

Bipolar, Schizophrenia GWAS Leads to Shared, Distinct Risk Variants

May 31, 2018

Rare Truncating Mutations Play Role in Neurodevelopmental Disease

May 18, 2018

Initial Data Bolsters Laguna Diagnostics' Plans for mRNA Psychiatric Diagnostic
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May 15, 2018

American Gut Project Reports Microbiome Results for 11K Participants

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Nucleotide Base Detected on Near-Earth Asteroid

Among other intriguing compounds, researchers find the nucleotide uracil, a component of RNA sequences, in samples collected from the near-Earth asteroid Ryugu, as they report in Nature Communications.

Clinical Trial Participants, Investigators Point to Importance of Clinical Trial Results Reporting in Canadian Study

Public reporting on clinical trial results is crucial, according to interviews with clinical trial participants, investigators, and organizers from three provinces appearing in BMJ Open.

Old Order Amish Analysis Highlights Autozygosity, Potential Ties to Blood Measures

Researchers in BMC Genomics see larger and more frequent runs-of-homozygosity in Old Order Amish participants, though only regional autozygosity coincided with two blood-based measures.

Suicidal Ideation-Linked Loci Identified Using Million Veteran Program Data

Researchers in PLOS Genetics identify risk variants within and across ancestry groups with a genome-wide association study involving veterans with or without a history of suicidal ideation.