beta-thalassemia At ESHG, Researchers Present New Noninvasive Prenatal Tests, Disease Recurrence Risk Study Scientists from the UK and China discussed two new NIPTs that include single-gene disorders and a study to estimate disease recurrence risk in families. Horizon Discovery, Rutgers Collaborate to Commercialize CRISPR Base Editing Technology The partners are planning to integrate the technology into Horizon's research tools and services and to develop it for applications in cell therapeutics. Singapore Team Develops Sequencing Method to Calculate Fetal Fraction for Targeted Prenatal Tests Premium The researchers plan to use the method in clinical research, designing noninvasive prenatal tests for single-gene disorders like beta thalassemia. St. Jude Study Reshapes Hemoglobin Genetic Disorders With CRISPR/Cas9 Editing Scientists introduced an indel to a promoter region to mimic a benign, naturally-occurring mutation that activated fetal hemoglobin production. Scientists Edit Beta-thalassemia Gene in Human Zygotes with CRISPR/Cas9 Though the edit was made in non-viable zygotes, the study wades into human germline engineering, a topic of great consternation for the CRISPR/Cas9 research community. Dec 15, 2011 Alnylam Presents Preclinical Data on Beta-Thalassemia, Erythropoiesis Efforts Premium Jul 28, 2011 Chinese Group Develops Melt Curve-PCR Assay for Beta-Thalassemia Genotyping Premium Dec 14, 2010 Sequencing Reveals Entire Fetal Genome in Maternal Plasma; Opens Door for Noninvasive Prenatal Tests Premium Breaking News FDA Revises SARS-CoV-2 Test Emergency Use Authorization Requirements to Account for Variants Geisinger Wins $5M NIH Grant to Develop Point-of-Care Genetic Diagnostic Tool Second Genome, Virginia Commonwealth University Partner on NASH Biomarker Discovery LGC Receives CE Mark for AccuPlex SARS-CoV-2, Flu A/B, RSV Reference Material Kit Esophageal Cancer Testing Firm Lucid Diagnostics Files For IPO Twist Bioscience, DeepCDR Collaborate on Antibody Library Design The Scan Booster for At-Risk The New York Times reports that the US Food and Drug Administration has authorized a third dose of the Pfizer-BioNTech SARS-CoV-2 vaccine for people over 65 or at increased risk. Preprints OK to Mention Again Nature News reports the Australian Research Council has changed its new policy and now allows preprints to be cited in grant applications. Hundreds of Millions More to Share The US plans to purchase and donate 500 million additional SARS-CoV-2 vaccine doses, according to the Washington Post. Nature Papers Examine Molecular Program Differences Influencing Neural Cells, Population History of Polynesia In Nature this week: changes in molecular program during embryonic development leads to different neural cell types, and more.