The international team of researchers also examined the genetic ties between personality traits and psychiatric disorders.
Using brain samples from individuals with or without autism spectrum disorder, researchers identified H3K27ac histone acetylation marks associated with ASD.
Using mitochondrial sequence data for hundreds of simplex families, investigators found predicted pathogenic heteroplasmic mutations were over-represented.
In Cell this week: double-strand breaks in the mouse genome, metabolomic features of yeast deletion strains, and more.
By focusing on sequences that have diverged rapidly in humans, researchers identified regulatory sequences suspected of affecting neural processes.
Using data from the Simons Simplex Collection, researchers estimated that 5 percent of autism spectrum disorder cases may involve mosaic de novo mutations.
In Nature this week: whole-genome sequencing of plasma DNA to study cancer gene expression, and more.
They found that hippocampal long-term potentiation triggered changes in protein signaling, including to a number of proteins linked to these disorders.
In Nature this week: loci linked to major depressive disorder, and more.
A comparative genomic study identified human-specific duplications at a chromosome 16p11.2 region implicated in autism and other conditions.
An analysis of UK Biobank data finds hemochromatosis to be more prevalent than thought, according to the BBC.
An analysis finds that female biomedical researchers receive fewer prizes than male ones, and when they do win prizes, they are less prestigious.
In Nature this week: improved genomic analysis using a graph genome reference, tumor mutational burden could predict clinical response to immune checkpoint inhibitors, and more.
Federal researchers tell the Los Angeles Times that the shutdown is causing missed research opportunities as they try to keep their experiments going.