Researchers found 7 percent of mutations in children's DNA could be traced to postzygotic mosaic mutations present early in their parents' embryonic development.
Investigators identified ties between autism spectrum disorder and mitochondrial haplogroups in mtDNA variant data from nearly 1,000 ASD-affected families.
In PNAS this week: deep evolutionary conservation of autism-linked genes, cytokine signature of chronic fatigue syndrome, and more.
The company is collaborating with hospitals to implement sequencing and machine learning approaches to pinpoint the molecular etiology of autism earlier in age.
In PNAS this week: analytical method for assessing shared variants, treatment targets in hereditary pancreatic cancer, and more.
Spectrum News reports that a group has uncovered a statistical flaw in a recent paper linking new genes to autism or developmental delay.
The consortium is collecting data from different omics streams for a cohort of individuals with autism spectrum disorders with the long-term goal of improving treatment.
In Genome Biology this week: genes linked to Hirschsprung disease, structural variant patterns in autism, and more.
One team examined single-nucleotide variation, indels, and copy-number variations in ASD, while the other focused on large structural variations.
Yale researchers find that autism risk-linked genes are also associated with increased cognitive ability, according to the Independent.
Nature News reports that gene therapy approaches are tackling sickle cell disease, but that the cost of treatment is a concern.
The Washington Post reports that a US Senate committee voted this week to approve the nomination of Stephen Hahn to lead the Food and Drug Administration.
One gene regulates hundreds of others to influence facial development, according to New Scientist.
In Nature this week: resources for single-cell analysis, little overlap in the microRNAs used by Salmonella and Shigella to infect host cells, and more.