autistic disorder

The consortium is collecting data from different omics streams for a cohort of individuals with autism spectrum disorders with the long-term goal of improving treatment.

In Genome Biology this week: genes linked to Hirschsprung disease, structural variant patterns in autism, and more.

One team examined single-nucleotide variation, indels, and copy-number variations in ASD, while the other focused on large structural variations.

Advantage, But Risk

Yale researchers find that autism risk-linked genes are also associated with increased cognitive ability, according to the Independent.

Two studies described de novo gene mutations involved in autism spectrum disorder and other neurodevelopmental conditions, while weeding out unrelated changes.

This Week in PLOS

In PLOS this week: signs of positive selection at autism-linked variants, gut microbiome difference between active and sedentary women, and more.

This Week in Nature

In Nature this week: Plasmodium genomes and evolution, novel developmental disorder loci, and more.

This Week in Cell

In Cell this week: study of circadian rhythms and the gut microbiome, zygotic reprogramming repair processes, and more.

University of Pennsylvania researchers found that patients with autism had a greater mutational burden in essential genes than their unaffected siblings.

This Week in Nature

In Nature this week: genome-wide transcriptome analysis of brain samples from people with autism spectrum disorder, flounder genome, and more.

Pages

An analysis of UK Biobank data finds hemochromatosis to be more prevalent than thought, according to the BBC.

An analysis finds that female biomedical researchers receive fewer prizes than male ones, and when they do win prizes, they are less prestigious.

In Nature this week: improved genomic analysis using a graph genome reference, tumor mutational burden could predict clinical response to immune checkpoint inhibitors, and more.

Federal researchers tell the Los Angeles Times that the shutdown is causing missed research opportunities as they try to keep their experiments going.