Researchers searched exome sequences of more than 100,000 individuals for associations to more than a dozen quantitative human traits and 10 diseases.
In Science this week: paternally inherited cis-regulatory structural variants in autism, and more.
Researchers found that children with autism are more likely to inherit cis-regulatory structural variants from their fathers than their unaffected siblings.
Researchers used mutations found among individuals with autism to tease out affected pathways, such as ones linked to synaptic function, morphology, and plasticity.
The company hopes to develop saliva-based RNA assays for concussion, Parkinson's disease and autism using biomarkers discovered by its two academic partners.
Speakers at HudsonAlpha's Genomic Medicine Conference said while sequencing results sometimes result in a diagnosis and change in care, they often have no consequence.
The researchers didn't find overall methylation differences between infants who later developed autism and those who did not.
The researchers conducted a genome-wide association study and other analyses using about 47,000 research participants from 23andMe.
In Science this week: genetic overlap between five psychiatric disorders, and more.
Using post-mortem data, researchers explored similarities and differences between autism, schizophrenia, bipolar disorder, alcoholism, and depression.
Bloomberg reports that the DNA-for-cash deal reported in Kentucky might be a more widespread scam.
St. Jude Children's Research Hospital scientists have treated infants with X-linked severe combined immunodeficiency using gene therapy in an early phase study.
St. Louis Public Radio reports that some African Americans are turning to DNA ancestry testing to help guide genealogical searches.
In Nature this week: a genomic analysis of the snailfish Pseudoliparis swirei, ancient DNA analysis gives insight into the introduction of farming to England, and more.