autistic disorder

Part of the autism advocacy organization's latest round of funding will support research aimed at developing protein biomarkers and better animal models.

Three grant types will support clinical, basic, and applied research using genomic and pharmacogenomic approaches, among others.

The company plans to develop and sell an autism risk test for children with older siblings who have already been diagnosed.

According to the grant abstracts, the project is "an unprecedented partnership" between two large-scale sequencing centers — at Baylor College of Medicine and at the Broad Institute — and a network of research labs focused on the genetics of autism, brought together by the Autism Genome Project and the Autism Consortium.

All three projects plan to use high-throughput sequencing to identify variants associated with autism or autism spectrum disorder.

Moving Target: CNVs in Disease

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More and more research is linking CNVs to disease. It's not only changing the way scientists study disease, but also how clinicians diagnose it.

New genetic studies suggest that SNPs and CNVs affecting neuronal cell adhesion — including one SNP that reached genome-wide significance in a large GWAS study — contribute to autism risk.

Quest, whose ClariSure test is based on a bacterial artificial chromosome array, is also considering adopting oligonucleotide array-based platforms sold by companies such as Affymetrix, Agilent Technologies, Illumina, and others.

The Recovery Act funds will fund genomics and biomarker studies for Autism disorders.

BioArray Briefs: 2009.03.24

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Quest Diagnostics, Centre for Proteomic and Genomic Research, SimuGen, Arrayit, Phalanx, Rosetta Biosoftware, Exiqon, Norgen Biotek, TcLand Expression, Genedata, GeneGo, Entelos, Integrated DNA Technologies, VH Bio, SciGene, Inter Medico

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An analysis of UK Biobank data finds hemochromatosis to be more prevalent than thought, according to the BBC.

An analysis finds that female biomedical researchers receive fewer prizes than male ones, and when they do win prizes, they are less prestigious.

In Nature this week: improved genomic analysis using a graph genome reference, tumor mutational burden could predict clinical response to immune checkpoint inhibitors, and more.

Federal researchers tell the Los Angeles Times that the shutdown is causing missed research opportunities as they try to keep their experiments going.