autistic disorder Analysis Estimates Psychiatric Disorder Risk from Specific Copy Number Variants in Danish Cohort The population-based analysis found that deletions and duplications in six genomic loci generally increased risk for autism spectrum disorder and ADHD. Children With Autism May Have Underdeveloped Gut Microbiomes, Metagenomic Analysis Finds The researchers are now developing a PCR-based diagnostic tool to evaluate the markers they found in a larger, independent cohort and across different populations. Gene-Disrupting Ultra-Rare Variants More Common in Children With Autism Spectrum Disorder The study's findings further support a multi-hit model for autism risk, especially among cases where autism runs in the family. Autism Sharing Initiative Brings Federated Data Model to Research, Clinical Care Premium DNAstack, Autism Speaks, and a Canadian-led coalition of hospitals, pharma companies, and patient advocates are turning to big data and GA4GH standards to raise understanding of autism. Analysis Uncovers Hundreds of Autism-Linked Genes Using Evolution-Informed Approach The evolutionary action-based approach could also predict which variants could contribute to more severe disease. Feb 8, 2021 Spatial Transcriptomics Study Refines View Across Layers of Human Brain Region Jan 19, 2021 Psychiatric Disorder Risk Affected by Dysregulation of RNA-Binding Proteins Jan 13, 2021 Autism Spectrum Disorder Study Finds Contribution From De Novo Tandem Repeat Mutations Jan 11, 2021 Mosaic Enhancer Mutations, CNVs Contribute to Risk of Developing Autism Jan 7, 2021 Identical Twins Have Non-Identical Genomes, Study Finds Dec 17, 2020 New Rhesus Macaque Reference Genome Holds Potential for Human Disease, Evolution Research Oct 29, 2020 De Novo, Inherited Autism Risk Factors Uncovered With SPARK Cohort Analysis Premium Oct 21, 2020 Gut Microbiome Analysis in Autistic Children Points to Detoxification Deficiencies Aug 24, 2020 Bionano Genomics Acquires Diagnostic Services Provider Lineagen for $9.6M Aug 10, 2020 Autism Subtype Marked by Abnormal Lipid Levels Uncovered in Analysis of Research, Healthcare Data Jul 27, 2020 Individuals With Autism More Likely to Have Expanded Tandem DNA Repeats May 14, 2020 Small Portion of Individuals With Autism Undergo Recommended Clinical Genetic Testing Apr 20, 2020 Loss-of-Function Mutation in BAF Subunit Gene Tied to Recessive Autism Feb 27, 2020 DNA Methylation Mapping in Genetic Syndromes Leads to Disease-Specific Episignatures Feb 7, 2020 Genetic Risk for Autism Associated With Neurodevelopmental Progress, Condition-Linked Traits Jan 31, 2020 Copy Number Variants May Influence Clinical Presentation Among Individuals with PTEN Mutations Jan 23, 2020 Autism Sequencing Study Uncovers New Disease-Associated Genes, Functional Clues Dec 27, 2019 SPARK Autism Research Initiative Obtains First Results, Explores New Recruitment Strategies Premium Dec 12, 2019 Psychiatric Disorders Fall Into Groups With Shared Genetic Contributors in GWAS Meta-Analysis Oct 15, 2019 Researchers Identify DNA Methylation Signature Linked to Aging, Autism in Children Load More Breaking News New Approach Identifies Candidate Causal Variants for Neuropsychiatric, Neurodevelopmental Conditions People in the News: Baylor's Thomas Caskey Dies; New Appointments at UK Biobank, CS Genetics, More In Brief This Week: Pathogenomix, Uniogen, Genetic Technologies, DnaNudge, Gravity Diagnostics, More New Products Posted to GenomeWeb: Biodesix, Curio Genomics, Akoya Biosciences, More NIH Earmarks $170M for All of Us Program's Personalized Nutrition Study Taiwanese Firm's IP Asserted in Suit Against Pacific Biosciences Found Partially Unpatentable The Scan Omicron's Sewage Path The New York Times writes that testing sewage is helping public health officials track Omicron. IBM Sells Part of Watson Health The Wall Street Journal reports IBM is selling part of its Watson Health business to an investment firm. Identifying the Right Whales The Boston Globe writes that genetic testing has helped identify North American right whales and find that weaning can take place earlier than thought. Science Papers on Approach to Quickly Sort Single Cells, Alternative Splicing in Cancer In Science this week: high-speed sorting of single cells using fluorescence imaging, and more.