autistic disorder
DNAstack, Autism Speaks, and a Canadian-led coalition of hospitals, pharma companies, and patient advocates are turning to big data and GA4GH standards to raise understanding of autism.
Analysis Uncovers Hundreds of Autism-Linked Genes Using Evolution-Informed Approach
The evolutionary action-based approach could also predict which variants could contribute to more severe disease.
Spatial Transcriptomics Study Refines View Across Layers of Human Brain Region
Spatial expression features in six layers of the human dorsolateral prefrontal cortex provided a look at laminar markers and discovered ties to neuropsychiatric disease genes.
Psychiatric Disorder Risk Affected by Dysregulation of RNA-Binding Proteins
Using a deep learning approach to study mutations in target sites of RNA-binding proteins, researchers identified DDHD2 as a candidate schizophrenia risk gene.
Autism Spectrum Disorder Study Finds Contribution From De Novo Tandem Repeat Mutations
The researchers found likely deleterious de novo tandem repeat mutations that were more common among individuals with autism spectrum disorder.