autistic disorder Study Links Maternal Mental Illness-Related Variants to Perinatal Risk Factors For Offspring Researchers identified relationships between pregnancy-related maternal traits and behaviors and polygenic risk scores for half a dozen mental health conditions. Autism-Linked Variants at Chromosome 16p Influence Nearby Gene Expression The chromosome arm is home to an excess of common, polygenic influences on autism risk as well as a CNV linked to the disorder. Autism, ADHD Found to Have Overlapping and Distinct Genetic Contributions Through a series of genome-wide association studies and other analyses, researchers uncovered seven shared genetic loci as well as five loci that differentiate the disorders. Early-Onset Psychosis Linked to Enhanced CNV Burden Researchers profiled CNVs in early-onset psychosis cases, uncovering a rise in copy number variants, including variants previously linked to other conditions. Autism Spectrum Disorder Studies Uncover Additional Genetic Risk Variants The two new studies relied on large sequencing cohorts to uncover moderate risk variants and variants that overlap with schizophrenia risk. Jun 2, 2022 Studies Spell Out Rare, Common Variant Contributions to Autism Spectrum Disorder Mar 14, 2022 Study Describes De Novo Mutation Detection With Long-Read Familial Sequence Data Feb 2, 2022 Organoid Study Sheds Light on How Autism Risk Gene Mutations Affect Brain Development Nov 24, 2021 Analysis Estimates Psychiatric Disorder Risk from Specific Copy Number Variants in Danish Cohort Jul 27, 2021 Children With Autism May Have Underdeveloped Gut Microbiomes, Metagenomic Analysis Finds Jul 26, 2021 Gene-Disrupting Ultra-Rare Variants More Common in Children With Autism Spectrum Disorder Jun 15, 2021 Autism Sharing Initiative Brings Federated Data Model to Research, Clinical Care Premium May 19, 2021 Analysis Uncovers Hundreds of Autism-Linked Genes Using Evolution-Informed Approach Feb 8, 2021 Spatial Transcriptomics Study Refines View Across Layers of Human Brain Region Jan 19, 2021 Psychiatric Disorder Risk Affected by Dysregulation of RNA-Binding Proteins Jan 13, 2021 Autism Spectrum Disorder Study Finds Contribution From De Novo Tandem Repeat Mutations Jan 11, 2021 Mosaic Enhancer Mutations, CNVs Contribute to Risk of Developing Autism Jan 7, 2021 Identical Twins Have Non-Identical Genomes, Study Finds Dec 17, 2020 New Rhesus Macaque Reference Genome Holds Potential for Human Disease, Evolution Research Oct 29, 2020 De Novo, Inherited Autism Risk Factors Uncovered With SPARK Cohort Analysis Premium Oct 21, 2020 Gut Microbiome Analysis in Autistic Children Points to Detoxification Deficiencies Aug 24, 2020 Bionano Genomics Acquires Diagnostic Services Provider Lineagen for $9.6M Aug 10, 2020 Autism Subtype Marked by Abnormal Lipid Levels Uncovered in Analysis of Research, Healthcare Data Jul 27, 2020 Individuals With Autism More Likely to Have Expanded Tandem DNA Repeats May 14, 2020 Small Portion of Individuals With Autism Undergo Recommended Clinical Genetic Testing Load More Breaking News Cancer Prognoses Informed by Module-Based Approach, Study Finds People in the News at Illumina, Centogene, BioSkryb New Products Posted to GenomeWeb: Bio-Rad, BD, Analytik Jena, BioMérieux Genetic Technologies to Raise A$5M in Direct Stock Offering In Brief This Week: SD Biosensors, Meridian, Oncocyte, Opko Health, GeneDx, More The Scan Study Reveals New Details About Genetics of Major Cause of Female Infertility Researchers in Nature Medicine conducted a whole-exome sequencing study of mote than a thousand patients with premature ovarian insufficiency. Circulating Tumor DNA Shows Potential as Biomarker in Rare Childhood Cancer A study in the Journal of Clinical Oncology has found that circulating tumor DNA levels in rhabdomyosarcoma may serve as a biomarker for prognosis. Study Recommends Cancer Screening for Dogs Beginning Age Seven, Depending on Breed PetDx researchers report in PLOS One that annual cancer screening for dogs should begin by age seven. White-Tailed Deer Harbor SARS-CoV-2 Variants No Longer Infecting Humans, Study Finds A new study in PNAS has found that white-tailed deer could act as a reservoir of SARS-CoV-2 variants no longer found among humans.