autistic disorder Autism Sharing Initiative Brings Federated Data Model to Research, Clinical Care Premium DNAstack, Autism Speaks, and a Canadian-led coalition of hospitals, pharma companies, and patient advocates are turning to big data and GA4GH standards to raise understanding of autism. Analysis Uncovers Hundreds of Autism-Linked Genes Using Evolution-Informed Approach The evolutionary action-based approach could also predict which variants could contribute to more severe disease. Spatial Transcriptomics Study Refines View Across Layers of Human Brain Region Spatial expression features in six layers of the human dorsolateral prefrontal cortex provided a look at laminar markers and discovered ties to neuropsychiatric disease genes. Psychiatric Disorder Risk Affected by Dysregulation of RNA-Binding Proteins Using a deep learning approach to study mutations in target sites of RNA-binding proteins, researchers identified DDHD2 as a candidate schizophrenia risk gene. Autism Spectrum Disorder Study Finds Contribution From De Novo Tandem Repeat Mutations The researchers found likely deleterious de novo tandem repeat mutations that were more common among individuals with autism spectrum disorder. Jan 11, 2021 Mosaic Enhancer Mutations, CNVs Contribute to Risk of Developing Autism Jan 7, 2021 Identical Twins Have Non-Identical Genomes, Study Finds Dec 17, 2020 New Rhesus Macaque Reference Genome Holds Potential for Human Disease, Evolution Research Oct 29, 2020 De Novo, Inherited Autism Risk Factors Uncovered With SPARK Cohort Analysis Premium Oct 21, 2020 Gut Microbiome Analysis in Autistic Children Points to Detoxification Deficiencies Aug 24, 2020 Bionano Genomics Acquires Diagnostic Services Provider Lineagen for $9.6M Aug 10, 2020 Autism Subtype Marked by Abnormal Lipid Levels Uncovered in Analysis of Research, Healthcare Data Jul 27, 2020 Individuals With Autism More Likely to Have Expanded Tandem DNA Repeats May 14, 2020 Small Portion of Individuals With Autism Undergo Recommended Clinical Genetic Testing Apr 20, 2020 Loss-of-Function Mutation in BAF Subunit Gene Tied to Recessive Autism Feb 27, 2020 DNA Methylation Mapping in Genetic Syndromes Leads to Disease-Specific Episignatures Feb 7, 2020 Genetic Risk for Autism Associated With Neurodevelopmental Progress, Condition-Linked Traits Jan 31, 2020 Copy Number Variants May Influence Clinical Presentation Among Individuals with PTEN Mutations Jan 23, 2020 Autism Sequencing Study Uncovers New Disease-Associated Genes, Functional Clues Dec 27, 2019 SPARK Autism Research Initiative Obtains First Results, Explores New Recruitment Strategies Premium Dec 12, 2019 Psychiatric Disorders Fall Into Groups With Shared Genetic Contributors in GWAS Meta-Analysis Oct 15, 2019 Researchers Identify DNA Methylation Signature Linked to Aging, Autism in Children Sep 25, 2019 Genetic Links Between Psychotic Experiences, Neuropsychiatric Diseases Uncovered in Study Sep 23, 2019 Autism Transcriptomic Analysis Uncovers Altered Gene Network Jun 19, 2019 Quadrant Biosciences Gets $330K NIH Grant to Continue Autism Dx Test Development Load More Breaking News Sequencing Study Uncovers MERS-Related Coronavirus in Swiss Bats Angstrom Bio Raises $3M in Private Financing Eagle Biosciences, Genetic Analysis Ink Distribution Agreement for Gut Microbiota Test Centogene Q1 Revenues Grow More Than Fivefold Driven by COVID-19 Testing Epizyme Partnering With Quest Diagnostics for Lymphoma Mutation Testing Enzo Biochem, CLX Health Partner to Support COVID-19 Testing for International Travel The Scan CDC Calls Delta "Variant of Concern" CNN reports the US Centers for Disease Control and Prevention now considers the Delta variant of SARS-CoV-2 to be a "variant of concern." From FDA to Venture Capital Former FDA Commissioner Stephen Hahn is taking a position at a venture capital firm, leading some ethicists to raise eyebrows, according to the Washington Post. Consent Questions Nature News writes that there are questions whether informed consent was obtained for some submissions to a database of Y-chromosome profiles. Cell Studies on Multimodal Single-Cell Analysis, Coronaviruses in Bats, Urban Microbiomes In Cell this week: approach to analyze multimodal single-cell genomic data, analysis of bat coronaviruses, and more.