atrial fibrillation Helix Showcases New Population Genomics Method in Cardiomyopathy Risk Study Premium Using a "sliding power window" method, the company found certain gene variant carriers with atrial fibrillation at higher risk for cardiomyopathies. Clinical Polygenic Risk Assay, Reporting Pipeline Shows Promise for Multiple Conditions Premium Researchers developed assays to assess PRSs for six common conditions, along with methods for sharing the results with doctors and patients. International Heart Rhythm Societies Set Out Recommendations on Genetic Testing for Cardiac Diseases The consensus statement, published this week, should help to guide decision-making around genetic testing for a variety of cardiac conditions. Cardiometabolic Disease Shows Ties to Depressive Mood, Irrespective of Genetic Risk Researchers saw an uptick in coronary artery disease, atrial fibrillation, and type 2 diabetes in individuals with frequent depressed mood across polygenic risk scores. IBM Watson, Broad Institute Expand Collaboration Into Heart Disease IBM and the Broad Institute will codevelop algorithms to apply artificial intelligence to predict cardiovascular risk from genomic and clinical data. Nov 7, 2018 Scripps-Nvidia Partnership Melding Genomics, Sensor Data Premium Aug 13, 2018 Broad Institute, Mass General Team Develops Polygenic Risk Scores for Five Common Diseases Jul 30, 2018 Massive Atrial Fibrillation GWAS Leads to 80 New Risk Loci Jun 27, 2018 Lifestyle, Genetics Independently Predict Cardiovascular Disease, Diabetes Risk Mar 21, 2018 Addition of Genetic Risk Score Improves Chances of IDing Atrial Fibrillation Patients, Study Finds Premium Dec 28, 2017 Atrial Fibrillation GWAS Provides Clues to Heart Condition Nov 27, 2017 European Consortium Aims to Deliver New Tests, Therapies for Cardiovascular Diseases Premium Apr 17, 2017 New Variants Linked to Atrial Fibrillation Risk Jun 22, 2016 Single SNP Mediates Some Differences in Atrial Fibrillation Risk Between Europeans, African Americans Apr 10, 2015 ARCA Stays Committed to Developing Heart Failure Rx with PGx Strategy despite Setbacks Premium Mar 10, 2015 Study Provides 'Strong Evidence' Backing Warfarin Initiation PGx Testing; Adoption Impact Unclear Premium Apr 16, 2014 Celera Researchers Investigating Genetic Risk Signature to Predict Atrial Fibrillation Premium Mar 6, 2014 Rosetta Data Links microRNA-150 to Atrial Fibrillation in Heart Failure Patients Premium Jan 8, 2014 FDA Accepts LabCorp's IDE Application for Atrial Fibrillation CDx Dec 4, 2013 Two Conflicting Prospective, RCTs on Warfarin PGx Provide No Definitive Guidance to Physicians Premium Oct 24, 2012 Study Suggests Two-Gene Combo Predicts Spectrum of Response to ARCA's Beta Blocker Gencaro Premium Dec 14, 2011 FDA Looks into Pradaxa Bleeding Risk; What Does it Mean for PGx-Guided Warfarin Dosing? Premium Oct 3, 2011 Warnex to Distribute DeCode Genetics Tests in Canada Mar 15, 2011 Xention to Study Biomarkers for AF Network Oct 27, 2010 When Might Warfarin PGx Be Better Than Pradaxa? Stakeholders Weigh In Premium Load More Breaking News Cedars-Sinai Sets Up $25M Single Cell Precision Medicine Center In Brief This Week: DermTech, Cerca Biotech, Colossal Biosciences, Biocept, Abbott, More Cue Health to Implement Shareholder Rights Plan BioMérieux Submits Dual FDA Marketing, CLIA Waiver Application for Respiratory, Sore Throat Panel GA4GH Announces 10 New 'Driver' Projects, Including First Pediatric Partner The Scan Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants. Small Study of Gene Editing to Treat Sickle Cell Disease In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms. Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema. Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.