atherosclerosis

Three microRNA that were significantly upregulated in plaques may serve as targets to affect cardiovascular disease development, according to a new study.

A Johns Hopkins team reported its finding in JAMA Cardiology, backed by SNP array data from 21,870 participants culled from several large cardiovascular studies.

Mungyeong mummy

A female mummy showing anatomical signs of atherosclerotic cardiovascular disease was found to carry risky versions of seven heart disease-related SNPs.

The firm has settled on a set of metabolite biomarkers, along with an algorithm, for its first version of a test for arterial plaque buildup.

The researchers will use TwoXar's software to predict potential candidates for atherosclerosis drugs and test them in pre-clinical studies.

The company's pipeline consists of tests for early detection of Alzheimer's and atherosclerosis as well as for guiding statin therapy.

Interleukin will provide its genetic tests for inflammatory and metabolic diseases for a study directed at a cardiovascular disease drug in development.

NEW YORK (GenomeWeb) – Cofactor Genomics said on Thursday it has won a contract from the National Heart, Lung, and Blood Institute and the National Human Genome Research Institute to identify sites of epigenetic modifications that contribute to cardiovascular disease endpoints.

NEW YORK (GenomeWeb) – New data published this month by researchers from Regulus Therapeutics and academic collaborators show that long-term therapeutic silencing of microRNA-33 could result in a number of deleterious effects in mice including fatty liver and elevated triglyceride levels.

NEW YORK (GenomeWeb News) – Global Genomics Group and Quintiles announced today a collaboration aimed at developing new diagnostic tools and treatments for cardiovascular diseases as part of the Genetic Loci and Burden of Atherosclerotic Lesions (GLOBAL) clinical study.

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The Wall Street Journal reports there is uncertainty surrounding whether He Jiankui's embryo editing did what he said it did.

Stat News reports that the pause on procuring fetal tissue for intramural US National Institutes of Health research will soon affect additional labs there.

Customers might want to consider what they might learn about their risk of diseases like Alzheimer's before snagging the genetic testing kits that are on many gift guides this year, NJ.com writes.

In Nature this week: genomic analysis of the invasive fall webworm, amp of constrained coding regions within the human genome, and more.