atherosclerosis Sema4, BioSymetrics Partner on Multiomic Drug Discovery The companies plan to apply AI technology to multiomic data in search of novel therapies for cardiovascular, neurological, and rare diseases. Genomics Plc Looks to Grow 'Genomic Prevention' With Polygenic Risk Scores Premium In two recent papers, the UK startup demonstrated the integration of polygenic risk scoring into primary care screening and workflows. Pharmacogenetic Testing for Statin Side Effects Doesn't Result in Worse Blood Cholesterol Levels Patients who underwent SLCO1B1 testing were able to lower their cholesterol levels similarly to those who did not, indicating that testing does not cause harm. UVA Teams Wins $2.7M NIH Grant to Study Genetic Variation in Atherosclerosis The scientists aim to use single-cell analysis to investigate the role of variation in a gene called ID3 in vascular smooth muscle cells. Liquid Biopsy Test Targets Early Detection of Diabetes Complications, Cancers Premium The researchers said the test performed well in distinguishing patients with or without complications and proved itself better than frequently used clinical variables. May 18, 2018 Atherosclerotic Plaques Reveal Differentially Expressed MicroRNAs Mar 7, 2018 Aortic Valve Stenosis GWAS Leads to Loci Also Tied to Heart Development, Atherosclerosis Oct 12, 2017 Cardiovascular Disease Risk Linked to mtDNA Copy Number Aug 17, 2017 Heart Disease Risk Alleles Reported In 17th Century Korean Mummy Mar 24, 2017 Omics Company Pursues LDT, FDA Routes for Mass Spec-Based CVD Test Premium May 25, 2016 University of Chicago, TwoXar Partner to Find New Cardiac Treatments Mar 9, 2015 Dx Firm Plaxgen Moving Plaque-based Alzheimer's, Atherosclerosis Tests toward Commercialization Premium Jan 7, 2015 Interleukin Genetics to Provide Testing Services to Isis for Clinical Study Sep 19, 2014 Cofactor Genomics Wins $300K Contract for Epigenetics Study of Cardiovascular Disease Jul 24, 2014 Regulus Study Points to Possibility of Adverse Effects with Chronic miR-33 Inhibition Premium Feb 19, 2014 Global Genomics, Quintiles Collaborate to Develop Genomic Tools for Cardiovascular Diseases Dec 19, 2013 New Data Link Atherosclerosis to microRNA with Atypical Biogenesis Mechanism Premium Sep 25, 2013 Illumina Partners with G3 on Study to ID Cardiovascular Disease Biomarkers, Drug Targets Nov 29, 2012 With Three Years of Cash in the Bank, Regulus Aims for Two INDs by 2014 Premium Aug 16, 2012 Regulus Inks microRNA Drugs Collaboration with AstraZeneca Premium May 17, 2012 Study Finds Genetic Testing Not Leading to Increased Use of Healthcare Services Jan 13, 2012 U of Virginia Team IDs Possible Biomarkers for Detecting Early Atherosclerosis Jun 9, 2011 Regulus Publishes Data Showing miR-33 Antagonism Impacts Atherosclerosis Premium May 24, 2011 NHGRI's ClinSeq Study Finds Clinically Relevant Results, but Challenges Remain Premium Apr 15, 2011 Quanterix, Gothenberg Researchers Show Potential Link Between Heart Attacks and Alzheimer's Marker Premium Load More Breaking News Verily Awarded CDC Contract for Wastewater Surveillance Genomic Health to Pay $32.5M to Resolve Cancer Test False Claims Allegations by DOJ Vela Diagnostics Inks Japan Distribution Agreement for HIV-1 Drug Resistance Tests Coronary Artery Calcification Contributors, Potential Drug Targets Found in Cross-Ancestry GWAS Max Planck Team Uses Spatial Single-Cell Proteomics Method to Analyze Hepatocyte Heterogeneity The Scan Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants. Small Study of Gene Editing to Treat Sickle Cell Disease In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms. Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema. Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.