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atherosclerosis

In PLOS this week: gene expression and epigenetics of Indonesian populations, hookworm parasite secretome, and more.

The scientists aim to use single-cell analysis to investigate the role of variation in a gene called ID3 in vascular smooth muscle cells.

The researchers said the test performed well in distinguishing patients with or without complications and proved itself better than frequently used clinical variables.

In PNAS this week: intronic STAT3 splice site linked to autosomal dominant primary immunodeficiency condition, human B lymphocyte changes following Epstein-Barr virus exposure, and more.

Three microRNA that were significantly upregulated in plaques may serve as targets to affect cardiovascular disease development, according to a new study.

Analyzing samples from Iceland and elsewhere, researchers uncovered one known and two new risk loci for aortic valve stenosis that are also associated with other heart risk pathways.

A Johns Hopkins team reported its finding in JAMA Cardiology, backed by SNP array data from 21,870 participants culled from several large cardiovascular studies.

Mungyeong mummy

A female mummy showing anatomical signs of atherosclerotic cardiovascular disease was found to carry risky versions of seven heart disease-related SNPs.

The firm has settled on a set of metabolite biomarkers, along with an algorithm, for its first version of a test for arterial plaque buildup.

The researchers will use TwoXar's software to predict potential candidates for atherosclerosis drugs and test them in pre-clinical studies.

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AstraZeneca has released its coronavirus vaccine trial protocol, according to the New York Times.

Time magazine looks into how liquid biopsies are changing cancer care.

According to the Guardian, more than 150 countries have signed on to a global SARS-CoV-2 vaccine plan.

In PNAS this week: similar muscle protein patterns across hypertrophic cardiomyopathy phenotypes, analysis of gene expression and brain anatomy in major depression, and more.