asthma | GenomeWeb


The Early Gut

The gut microbiome appears to have a role in infants' later risk of developing allergies and asthma, a new study says.

The findings could lead to a more personalized approach for preventing asthma in children, the researchers suggested.

Despite initial enthusiasm, the majority of enrollees haven't stayed engaged with the app and relatively few have submitted genetic data from 23andMe.

Researchers found that children who have taken macrolide antibiotics have distinctive microbiomes and that some of those changes are persistent.

Four bacterial genera are found at lower levels in the gut microbiomes of three-month-old infants believed to be at risk of developing asthma later in life.

Data for tens of thousands of UK Biobank participants revealed an overlapping set of variants involved in airflow obstruction in heavy and never smokers. 

This Week in Science

In Science this week: yeast spliceosome structure, and more.

Under the agreement, Abbott will create tests for two protein biomarkers that AstraZeneca hopes can predict asthma patients' response to its investigational drug tralokinumab.

A team from Cincinnati Children's Hospital Medical Center has linked the expression of VNN1 to how well pediatric asthma patients respond to corticosteroid treatment.

The researchers are working on an electronic genetic counseling platform that will be in later versions of the app.


In Nucleic Acids Research this week: ProTraits includes genetic, phenotypic data on bacteria, archaea; Candida albicans assembly 22; and more.

The Wall Street Journal reports that researchers are looking beyond Cas9 for CRISPR editing.

Familial DNA searches in criminal cases are winning over some critics, the Los Angeles Times reports.

In PNAS this week: miR-515 levels higher in women with preeclampsia, horizontal gene transfer in parasitic plants, and more.