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Among the study's aims is determining how rates of SARS-CoV-2 infection differ between healthy children and ones with asthma or other allergic conditions.
In PNAS this week: population genomics study on indigenous individuals in Brazil, programmable genome-editing approach, and more.
A missense change in a gene coding for an androgen production enzyme had apparent ties to poor lung function and reduced glucocorticoid drug response.
A new partnership and licensing agreement will help the research institute aggregate genotype and phenotype data for the NIH-funded PreCISE Network asthma program.
With RNA sequence data on thousands of individual lung cells, researchers fleshed out new and known cell clusters, before digging into cell state and cellular interaction changes in asthma.
These loci include a known asthma locus at 17q12-q21, but also loci at 8p23 and 8q24 that could be specific to asthma risk among individuals of African ancestry.
The company, which employs 300 people, axed 30 jobs in the US and 25 jobs from its overseas operations as it refocuses on therapeutic development.
The researchers will combine genomic analysis with environmental and mobile device data from 1,200 participants to try to better understand the disease.
The company is marketing the panel, which runs on NanoString Technologies' nCounter System, to chemical and cosmetics firms as a replacement for animal models.
The partners aim to identify genetic factors common to individuals with asthma and asthma-chronic obstructive pulmonary disease overlap syndrome.
Nature News reports that genomics is being applied to trace and try to prevent additional COVID-19 waves.
Rady's Children Hospital and San Diego County are teaming up to test pediatric patients and their families for COVID-19 to gauge the spread of the virus locally, according to the San Diego Union-Tribune.
Wildlife managers aim to boost the genetic diversity of Mexican gray wolves by placing captive-born foster pups into packs with similarly aged wild pups, the Mercury News reports.
In Science this week: Genetic Probability tool identifies likely diagnoses in 45 percent of inflammatory arthritis cases, and more.