Penn bioinformaticians are testing REALGAR, an application to simplify searches of GWAS, WGS, RNA-seq, and other test results for wet-lab researchers.

This Week in Nature

In Nature this week: Armillaria fungal genomes; risk variants linked to asthma, eczema, and hay fever; and more.

A genome-wide association meta-analysis involving hundreds of thousands of individuals led to 130 new and known risk variants linked to all three allergic conditions.

Researchers identified rises and declines in disease risk that appeared to coincide with the proportion of ancestry from Mapuche and Aymara populations.

This Week in PLOS

In PLOS this week: mitochondrial mutation linked to tubulointerstitial kidney disease, asthma protection variant, and more.

This Week in PLOS

In PLOS this week: nasal microbial communities in asthma patients; sequencing-based way to detect, track schistosomiasis; and more.

The Early Gut

The gut microbiome appears to have a role in infants' later risk of developing allergies and asthma, a new study says.

The findings could lead to a more personalized approach for preventing asthma in children, the researchers suggested.

Despite initial enthusiasm, the majority of enrollees haven't stayed engaged with the app and relatively few have submitted genetic data from 23andMe.

Researchers found that children who have taken macrolide antibiotics have distinctive microbiomes and that some of those changes are persistent.


Robert Redfield is floated as the next director of the US Centers for Disease Control and Prevention, the Washington Post reports.

The New York Times writes that the National Institutes of Health's All of Us Research Program is "ambitious" and that some are concerned it might be overly so.

Representative Lamar Smith's criticism of the National Science Foundation has "changed the nature of the conversation," according to ScienceInsider.

In PLOS this week: non-coding RNA function in yeast, transcriptomic profiles of malaria parasites, and more.