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aortic aneurysm

Abdominal Aortic Aneurysm Genetic Study Finds Lipid Metabolism Loci, Potential Drug Target

A large genome-wide association study meta-analysis unearthed disease-associated genes and pathways and suggested PCSK9 inhibitors as a potential treatment.

Machine-Learning Approach Predicts Abdominal Aortic Aneurysm Risk From Genomic Data

The framework, called HEAL, could be used as an early screening test for AAA and as a personal health management tool. In addition, it may be applicable to other complex diseases.

Genetic Study Supports Potential Lipid Role in Aortic Cardiovascular Condition

Using genetic risk scores, researchers uncovered apparent associations between abdominal aortic aneurysm and cholesterol or triglyceride levels.

Missense LOX Mutation Linked to Aortic Rupture, Aneurysm

The researchers also developed a mouse model of the mutation using CRISPR/Cas9 genome engineering to examine its effects.

Pennsylvania Health Department Funds Translational 'Omics Projects

NEW YORK (GenomeWeb News) – Pennsylvania's Department of Health has awarded several million dollars in funding to research institutes and clinical science centers in the state that seek to translate genomics research for clinical use.