A genome-wide association study meta-analysis of eight psychiatric conditions led to new and known risk loci, and revealed three distinct groups of conditions.
A large genome-wide association meta-analysis and follow-up analyses revealed eight risk loci involving SNPs previously associated with body traits, metabolism, and psychiatric risk.
NEW YORK (GenomeWeb News) – Researchers from the University of Iowa and the University of Texas Southwestern Medical Center have uncovered variants in two related genes that appear to be associated with the risk of developing an eating disorder.
By genotyping more than 1,000 individuals with anorexia nervosa and almost 4,000 unaffected controls, researchers have identified common SNPs and rare CNVs that appear to be linked to the condition.
Their results, detailed this month in PLoS ONE, suggest that this approach — sequencing, at a high depth, chromosomal regions identified by linkage tests — may be a good method for identifying genes in hereditary disease.
In PNAS this week: altered gene expression in brain samples from Alzheimer's disease patients, effects of gene mutations found in bladder cancer, and more.
