Angelman syndrome Australian Researchers Adapt Melt Curve Methylation Test for Infant Rare Genetic Disorder Screening Premium The test combines melt curve analysis and high-throughput, quantitative PCR to detect Prader-Willi, Angelman, and Dup15q syndromes in infants. DNA Methylation Mapping in Genetic Syndromes Leads to Disease-Specific Episignatures Researchers identified 34 episignatures that could be used for diagnostic testing and the interpretation of ambiguous genetic test results. Ovid Therapeutics, NeuroPointDX Form Biomarker Partnership The companies will work together to identify novel biomarkers of the rare genetic disorder Angelman syndrome. BioArray Briefs: 2009.03.31 Premium Baylor College of Medicine, Illumina, Aushon Biosystems, SciGene, Invitrogen Baylor to Use Illumina's Infinium Products in Developmental Diseases Studies Baylor will use the arrays for studying genomic imprinting and its role in developmental diseases. Feb 25, 2009 Quest Licenses Another Epigenomics Biomarker Breaking News NanoString, A*Star, Next Level Genomics to Launch Spatial Biology Laboratory in Singapore FDA Approves Entrogen's RAS Mutation Detection Kit as CDx for Vectibix Cancer Predisposition Variants Increase Secondary Cancer Mortality Risk in Pediatric Survivors BostonGene, Johns Hopkins University Partner for Multiple Cancer Clinical Research Projects KromaTid, Noble Life Sciences Ink Distribution, OEM Agreement The Scan Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants. Small Study of Gene Editing to Treat Sickle Cell Disease In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms. Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema. Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.