anemia

Researchers treated a fetus with a severe genetic disorder while still in the womb, according to the New York Times.

Base Correction

Using base editing, a Chinese research team has repaired a β-thalassemia-causing mutation in cloned embryos, Nature News reports.

VISION aims to provide validated regulatory modules, quantitative models for gene regulation, and guides for translating research from mouse models to human.

A modified version of a commercially available magnetic bead cell sorting instrument from Miltenyi Biotec could be deployed to areas without cGMP facilities.

The team at Cincinnati Children’s Hospital Medical Center was able to override errors in the FA DNA repair pathway, allowing the cells to grow normally.

This Week in PNAS

In PNAS this week: decreased DOCK4 expression in myelodysplastic syndromes plus anemia, hepatitis A evolution, and more.

Researchers sequenced samples from hundreds of individuals with aplastic anemia to narrow in on somatic mutation and clonal evolution patterns in the disease.

The Global Globin 2020 Challenge will promote the collection and sharing of genomic data, especially in low- and middle-income countries most affected by hemolytic anemias.

This article has been updated to correct the name of Intrinsic's CEO.

Alnylam Pharmaceuticals this week provided an update to its research and development activities, adding a new preclinical program to its pipeline with ALN-AS1 for acute intermittent porphyria while dropping its refractory anemia drug ALN-HPN in order to focus on “higher priority”

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An artificial intelligence-based analysis suggests a third group of ancient hominins likely interbred with human ancestors, according to Popular Mechanics.

In Science this week: reduction in bee phylogenetic diversity, and more.

The New York Times Magazine looks into paleogenomics and how it is revising what's know about human history, but also possibly ignoring lessons learned by archaeologists.

The Economist reports on Synthorx's efforts to use expanded DNA bases they generated to develop a new cancer drug.