anemia

Base Correction

Using base editing, a Chinese research team has repaired a β-thalassemia-causing mutation in cloned embryos, Nature News reports.

VISION aims to provide validated regulatory modules, quantitative models for gene regulation, and guides for translating research from mouse models to human.

A modified version of a commercially available magnetic bead cell sorting instrument from Miltenyi Biotec could be deployed to areas without cGMP facilities.

The team at Cincinnati Children’s Hospital Medical Center was able to override errors in the FA DNA repair pathway, allowing the cells to grow normally.

This Week in PNAS

In PNAS this week: decreased DOCK4 expression in myelodysplastic syndromes plus anemia, hepatitis A evolution, and more.

Researchers sequenced samples from hundreds of individuals with aplastic anemia to narrow in on somatic mutation and clonal evolution patterns in the disease.

The Global Globin 2020 Challenge will promote the collection and sharing of genomic data, especially in low- and middle-income countries most affected by hemolytic anemias.

This article has been updated to correct the name of Intrinsic's CEO.

Alnylam Pharmaceuticals this week provided an update to its research and development activities, adding a new preclinical program to its pipeline with ALN-AS1 for acute intermittent porphyria while dropping its refractory anemia drug ALN-HPN in order to focus on “higher priority”

Researchers using exome sequencing to study ADHD found rare mutations they think may be causing a patient's anemia, raising the question of how to handle unrelated findings in sequencing studies.

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A new analysis examines the gender gap among paper authors in the sciences and says it may take decades or more to close.

Researchers have uncovered signals of selection that may enable the Bajau people to free five hundreds of feet deep, Reuters reports.

In Science this week: paternally inherited cis-regulatory structural variants in autism, and more.

A new report outlines issues facing the implementation of personalized medicine in the UK, the Independent reports.