anemia | GenomeWeb

anemia

A modified version of a commercially available magnetic bead cell sorting instrument from Miltenyi Biotec could be deployed to areas without cGMP facilities.

The team at Cincinnati Children’s Hospital Medical Center was able to override errors in the FA DNA repair pathway, allowing the cells to grow normally.

This Week in PNAS

In PNAS this week: decreased DOCK4 expression in myelodysplastic syndromes plus anemia, hepatitis A evolution, and more.

Researchers sequenced samples from hundreds of individuals with aplastic anemia to narrow in on somatic mutation and clonal evolution patterns in the disease.

The Global Globin 2020 Challenge will promote the collection and sharing of genomic data, especially in low- and middle-income countries most affected by hemolytic anemias.

This article has been updated to correct the name of Intrinsic's CEO.

Alnylam Pharmaceuticals this week provided an update to its research and development activities, adding a new preclinical program to its pipeline with ALN-AS1 for acute intermittent porphyria while dropping its refractory anemia drug ALN-HPN in order to focus on “higher priority”

Researchers using exome sequencing to study ADHD found rare mutations they think may be causing a patient's anemia, raising the question of how to handle unrelated findings in sequencing studies.

The assay, which its developers claim can measure telomere length in less than half the time of other PCR-based methods while using 20-fold less genetic material, will be deployed as part of a clinical study designed to monitor changes in telomere length in response to certain therapies in patients with telomere diseases.

The company also disclosed that it and partner Cubist Pharmaceuticals have decided to put on hold the development of a second-generation version of Alnylam's respiratory syncytial virus treatment, although no details regarding the decision were provided.

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In Science this week: genetic target for urothelial bladder cancer treatment, and more.

At the Conversation, the University of Oxford's Michael Macklay writes that learning genetic risk of disease is a personal decision.

Two dozen scientific organizations have endorsed the March for Science, according to ScienceInsider.

Researchers in Japan describe a chimpanzee with a chromosomal abnormality similar to human Down syndrome, Mashable reports.