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Alzheimer's disease

The Phase 2 grant is for work the company is doing to analyze the proteomic responses of immune cells in patients with Alzheimer's and related conditions.

In PLOS this week: transcriptomics-based strategy to study Alzheimer's disease heterogeneity, insecticide resistance diversity and evolution, and more.

The company's adaptive low-resource testing technology requires no instrumentation and limited equipment, making it adaptable to settings without clinical lab infrastructure.

The study also found that certain genes may influence multiple complex traits, while others only affect one phenotype, making them worthwhile therapeutic targets.

The charity also announced a partnership with Sage Bionetworks to establish an online repository for biomarker data generated by grant recipients.

Risk and Protection

People with the APOE e4 gene variant who are at an increased risk for Alzheimer's disease but who are also heterozygous for a Klotho haplotype may have a reduced disease risk, a new study has found.

Brain samples from Alzheimer's cases and controls revealed an energy metabolism-related protein network with ties to microglia and astrocyte activity.

The company will offer a 32-gene polygenic score test to patients in the Osaka, Japan Nakanoshima Clinic, with reporting and patient support help from IxLayer.

Plan for Alzheimer's

The governor of New York has proposed a five-year plan to study the genomes of people with or who are at high risk of developing Alzheimer's disease.

The five-year initiative aims to collect and disseminate genomic data on 1 million people with Alzheimer's disease or who are at risk for the condition.

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The Washington Post reports on researchers' efforts to determine the effect of an increasingly common SARS-CoV-2 mutation.

Florida Politics reports Florida's law barring life, long-term care, and disability insurers from using genetic information in coverage decisions went into effect at the beginning of July.

A new analysis finds a link between popular media coverage of a scientific study and how often that paper is cited.

In Nature this week: CRISPR approaches to editing plant genomes, way to speed up DNA-PAINT, and more.