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Alzheimer's disease

A 26-year-old woman tells Cosmopolitan about learning her APOE status at a young age.

The bill would provide additional funding to each NIH institute and center, and would follow a 5.4 percent budget increase received in fiscal 2019.

The blood-based test is designed to detect changes in levels of microRNAs that are enriched in specific brain regions affected by Alzheimer's disease.

For a Breakthrough

Winners of this year's Breakthrough Prize in the life sciences include researchers who studied neurodegenerative disorders and protein folding.

Investigators identified dozens of Alzheimer's-related epigenetic signatures based on cytosine methylation and other profiles in Alzheimer's-related cell lines and patient samples.

NanoView will develop custom antibody-based assays on its ExoView platform to identify EVs containing biomarkers potentially linked to the neurological disorders.

In Science this week: approach to infer genotype-by-environment interaction from genetic variants associated with phenotypic variability, and more.

And Now You Know

NPR speaks with research participants before and after they learn their APOE E4 status, which affects their risk of developing Alzheimer's disease.

Of participants with high genetic risk, 1.13 percent with a favorable and 1.78 percent with an unfavorable lifestyle developed dementia over a median eight years.

Individuals with Alzheimer's disease are enriched for somatic mutations in brain tissue that affect tau-related pathways, as compared to unaffected individuals.

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In PLOS this week: preconception carrier screening program results, comparative genomics-based analysis of Elizabethkingia meningoseptica, and more.

Canadian regulators are beginning to share information from new drug studies, Undark reports.

In a column at the Dallas Morning News, the Stanley Medical Research Institute's E. Fuller Torrey says the Human Genome Project hasn't delivered on promised results.

Researchers explore a possible genetic cause for some cases of sudden infant death syndrome, KOMO News reports.