Alzheimer's disease
Protective, Risk-Linked APOE Alleles Affect Glial Cell Transcriptome
The APOEε4 allele is linked to the upregulation of a phagocytosis and proinflammatory gene set both in normal aging and Alzheimer's disease brains.
Infinity BiologiX to Offer Cytox Alzheimer's Disease Genetic Risk Test in US
Based on Cytox's GenoScore platform, IBX will provide a laboratory-developed test at its CLIA-certified, CAP-accredited lab in Piscataway, New Jersey.
Alzheimer's Disease Meta-Analysis Identifies Novel Differentially Methylated Loci
Combined data from six Alzheimer's studies identified differential DNA methylation in different brain regions and across the cortex.
NIH, Genomics England Launch Large-Scale Human Genome Sequencing Studies Using Nanopore Technology
The research projects will use Oxford Nanopore Technologies' PromethIon 48 instrument to sequence genomes of patients with dementia and cancer, respectively.
Alzheimer's Disease Genomes Lead to Novel Loci Involved in Synaptic Function
Starting with genome sequences for thousands of individuals from Alzheimer's-affected families, researchers found rare disease-associated variants at 13 new loci.