Researchers found that about 17 percent of sporadic amyotrophic lateral sclerosis patients harbor at least one deleterious rare variant or repeat expansion.
Rare mutations in the ANXA11 gene showed up in cases with familial and sporadic forms of amyotrophic lateral sclerosis.
Poly(GP) proteins could be detected within ALS patients samples and used to determine whether ALS drugs under development are reaching their targets.
Experts led by Duke neuroscientist Allen Roses developed the database hoping to boost researchers' ability to explore the role of short structural variants in complex diseases.
In Nature this week: variant linked to obesity risk in Samoans, health of cloned animals, and more.
The researchers particularly highlighted C21orf2 and NEK1, which are involved in cilial and mitochondrial function.
In Science this week: genomes from the Fertile Crescent give insight into early farmers, and more.
The firms said their test will be developed to detect levels of the tau protein that can leak into a person's bloodstream after head trauma or injury.
The New York Genome Center will sequence genomes of patients who died of ALS and who have donated tissue samples to Target ALS.
Under the Genomic Translation for ALS Clinical Care project, the partners will perform next-generation sequencing and clinical phenotyping on 1,500 ALS patients.
Gene drives might run into biological resistance, the Economist reports.
Forensic experts exhumed painter Salvador Dalí's body to collect DNA for a paternity test, CBS News reports.
Yale Environment 360 writes that synthetic and conservation biologists aren't always on the same wavelength, but they are trying to reach an understanding.
In Science this week: full CRISPR locus integration complex structure, and more.