ALS New ALS Risk Gene Suggests Role for Apoptosis Rare variants in the TP73 gene affect protein function, increase apoptosis, and lead to the impaired development of motor neurons, according to a new study. Nonprofit Target ALS Launches $15M Biomarker Research Initiative The money will be used to fund amyotrophic lateral sclerosis biomarker research, a natural history study, and a biosample and genomics core. Brain Proteins May Mediate Effects of Genetic Variants on Some Neurological Phenotypes The study also found that certain genes may influence multiple complex traits, while others only affect one phenotype, making them worthwhile therapeutic targets. Medidata, Project ALS Form Research Alliance The partners will use Medidata's machine learning-based biomarker discovery platform to investigate the amyotrophic lateral sclerosis disease process. ALS Genomic Analysis Highlights Potential MicroRNA Contributor Feb 4, 2019 New York Genome Center Receives $6M From ALS Association, Tow Foundation Sep 7, 2018 Asuragen ALS, Dementia Assay Gets Favorable Evaluation From UPenn Team Premium Jul 24, 2018 NYGC's MetroNome Visualization Tool Aims to Integrate Different Data Types Premium Jul 16, 2018 Verge Genomics Scores $32M in Series A Round Apr 9, 2018 Sporadic ALS Risk Appears to Overlap Slightly With Other Neurodegenerative Conditions Apr 6, 2018 Amarantus Reacquires Neurology Diagnostic Assets from Avant Mar 21, 2018 Loss-of-Function KIF5A Mutations Linked to Amyotrophic Lateral Sclerosis Dec 11, 2017 RowAnalytics' Giro Initiative Brings Precision Medicine Perspective to Neurodegenerative Disorders Premium Nov 21, 2017 Illumina-Developed Software Helps Find Repeat Expansions to Aid Disease Detection Premium Oct 10, 2017 Oxford BioDynamics Advances Epigenetic Signatures for Breast Cancer, ALS Premium Sep 22, 2017 Verge Genomics Forms ALS Research Collaboration Aug 11, 2017 ALS Study Sees Blood Methylation Differences Between Twins Discordant for Disease Aug 10, 2017 Researchers Use CRISPR to Destroy Pathogenic RNA Species Linked to Huntington's Disease, ALS Jun 22, 2017 Novel Variants in ALS-Linked Genes Found in Sporadic Cases of Disease May 3, 2017 ALS Associated With Defects in Vesicular Trafficking Protein Mar 30, 2017 Protein Marker for Amyotrophic Lateral Sclerosis Uncovered Sep 22, 2016 New Public Database of Short Structural Variants Helps Researchers Pinpoint ALS Risk Marker Jul 25, 2016 Novel ALS Susceptibility Variants Uncovered in Pair of Studies Mar 30, 2016 ADx NeuroSciences, Quanterix Ink Deal to Develop Blood-Based Concussion Test Sep 24, 2015 ALS Association Heads Collaboration on Postmortem WGS of ALS Patients Load More Breaking News SUPER Psychosis Study Presented at ASHG Digs Into Relationships of Rare Variants, Phenotypes People in the News: New Appointments at Myriad Genetics, Becton Dickinson, Delfi Diagnostics, More In Brief This Week: Virginia Commonwealth University, Dovetail Genomics, Lucid Diagnostics, and More New Products Posted to GenomeWeb: Bio-Rad, PerkinElmer, Ares Genetics, Purigen Biosystems, More Genetron Health, Fosun Ink Commercialization Deal for Seq-MRD Test in China MultiMuTHER Team Tracks Expression, Metabolite Relationships in Aging TwinsUK Participants The Scan More Boosters for US Following US Food and Drug Administration authorization, the Centers for Disease Control and Prevention has endorsed booster doses of the Moderna and Johnson & Johnson SARS-CoV-2 vaccines, the Washington Post writes. From a Pig A genetically modified pig kidney was transplanted into a human without triggering an immune response, Reuters reports. For Privacy's Sake Wired reports that more US states are passing genetic privacy laws. Science Paper on How Poaching Drove Evolution in African Elephants In Science this week: poaching has led to the rapid evolution of tuskless African elephants.