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alcohol dependence

A genome-wide meta-analysis involving more than 435,000 individuals also linked problematic alcohol use with other substance abuse and psychiatric disorders.

In Science this week: potentially pathogenic mutations found in hematopoietic stem cells from young healthy donors, and more.

A genome-wide association study uncovered six loci associated with heavy drinking and additional analysis found ties to other conditions including lung cancer.

The partners are working under NIAAA grants to identify genetic markers to help predict response to the drug acamprosate, which is used as a treatment for alcoholism.

Eurofins Scientific will help Adial validate a companion diagnostic for a drug being developed and identify patients for enrollment into a Phase III trial.

Drinking-Linked Loci

A genome-wide association study uncovers genetic variants linked with excessive drinking and alcoholism.

An international team found 566 variants in 406 loci, 150 of which evidenced pleiotropic association for alcohol and tobacco use.

A study in Microbiome finds that heavy drinkers have an unhealthy mix of bacteria in their mouths.

In Science this week: genetic overlap between five psychiatric disorders, and more.

Using post-mortem data, researchers explored similarities and differences between autism, schizophrenia, bipolar disorder, alcoholism, and depression.

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The World Health Organization will be providing low-cost COVID-19 tests to low- and middle-income nations, according to Reuters.

Nature News examines how the confirmation of Amy Coney Barrett to the US Supreme Court could affect scientific agencies.

Nobel Prize-winner Arthur Ashkin, who developed optical tweezers, has died at 98, the Washington Post reports.

In PNAS this week: altered gene expression in brain samples from Alzheimer's disease patients, effects of gene mutations found in bladder cancer, and more.