alcohol dependence Tobacco, Alcohol Use Contributors Uncovered With Multi-Ancestry GWAS Researchers unearthed more than 3,800 tobacco or alcohol use-related variants using data for 3.4 million participants from four ancestry groups. Alcohol Abuse Genetic Study Implicates Additional Variants in Risk of Problem Drinking A genome-wide meta-analysis involving more than 435,000 individuals also linked problematic alcohol use with other substance abuse and psychiatric disorders. Study Identifies Loci Associated With Alcohol Consumption, Explores Links to Other Conditions A genome-wide association study uncovered six loci associated with heavy drinking and additional analysis found ties to other conditions including lung cancer. Hazelden Betty Ford Foundation, Mayo Clinic to Study Pharmacogenomics of Alcoholism Treatment The partners are working under NIAAA grants to identify genetic markers to help predict response to the drug acamprosate, which is used as a treatment for alcoholism. Adial Pharmaceuticals, Eurofins Scientific Partner on CDx for Alcohol Use Disorder Drug Eurofins Scientific will help Adial validate a companion diagnostic for a drug being developed and identify patients for enrollment into a Phase III trial. Jan 15, 2019 Hundreds of Genetic Variants Implicated in Tobacco, Alcohol Use Feb 8, 2018 Brain Transcriptome Distinctions, Overlaps Characterized in Neuropsychiatric Conditions Oct 25, 2017 Overlapping Alcohol Dependence, Major Depression Risk Locus Detected Jul 7, 2015 Affymetrix, BioRealm, RUCDR Ally to Genotype NIDA Biobank Dec 5, 2014 U of Texas Transcriptome Study Reveals Gene Networks Related to Alcoholism Premium May 20, 2014 Researchers Link Panel of Genes to Alcoholism Risk Nov 22, 2013 Combined GWAS, Protein Network Analysis Reveals Genes Contributing to Alcohol Dependence Nov 11, 2013 NIH to Commit $7.5M for Alcoholism Risk Genetics Project Oct 10, 2013 Tekmira Adds HBV to Pipeline, Aims to Move Drug into Clinic in '14 Premium Aug 30, 2013 NIH to Fund Projects Focused on Genetic, Epigenetic Basis of Drug and Alcohol Co-addiction Oct 25, 2012 NIAAA to Fund Brain Bank Center for Alcohol Studies Mar 12, 2012 International Partners to Seek Genes Involved in Cirrhosis Mar 1, 2012 Tekmira Expands Pipeline, Extends Cash Runway into 2013 Premium Dec 2, 2011 Rutgers Lands $10M for Alcoholism Genetics and Behavior Study Jul 22, 2011 NIH to Fund Substance Use Gene-Environment Studies Mar 28, 2011 NIH to Fund DNA Data, Sample Storage Sep 3, 2010 NIAAA Provides $2.5M in SBIR and STTR Funding for Research Into Biomarkers of Alcohol Use Premium Aug 30, 2010 NIH to Fund Research on Alcohol-related Biomarkers May 26, 2010 UC Berkeley Fends off DTC Genomics Critics; Other Schools Mull Genetic Tests as Educational Tools Premium Apr 29, 2009 VCU Opens Molecular Medicine Research Center Breaking News New Products Posted to GenomeWeb: Qiagen, Thermo Fisher, Bionano Genomics, BillionToOne, More People in the News at Illumina Ventures, Element Biosciences, Epigenomics, Exagen, More Genomic Approaches Boost Rare Disease Diagnoses in Middle Eastern Patient Population GeneDx to Raise $150M in Public and Direct Stock Offerings In Brief This Week: T2 Biosystems, Novacyt, OpGen, Dante Genomics, Nautilus Biotechnology, More The Scan Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups. Genome-Wide Analysis Sheds Light on Genetics of ADHD A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder. MicroRNA Cotargeting Linked to Lupus A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus. Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.