aging Clonal Hematopoiesis Linked to Common, Rare Genetic Variants Analyzing almost 628,400 exome sequences, researchers found common and rare variants corresponding with different forms of clonal hematopoiesis of indeterminate potential. Regulatory Alterations Overrepresented in Single-Cell Sequence Data From Individual Neurons Researchers profile somatic mutation patterns in individual neurons from the prefrontal cortex using new and published single-cell sequences spanning 17 individuals. Age Labs, BioAge to Mine Norwegian Biobank Cohort to Produce New Diagnostics, Drugs Premium The partnership will see the two companies scour a Norwegian biobank for data that could produce a multitude of new aging-related tests, therapies, and perhaps companion diagnostics. Heart Dysfunction Insights Drawn From Age-Related Cardiomyocyte Mutations Researchers used single-cell whole-genome sequencing to track somatic point mutations in heart cardiomyocytes in samples from infants to elderly individuals. Imagene Labs, Kalbe Partner for Genetic Risk Tests Kalbe is launching two new tests that employ ancestry-based genetic risk scoring technology developed by Imagene Labs in Singapore. Apr 20, 2022 Advanced Alzheimer's Disease Linked to Somatic Mutation Rise in Neuronal Cells Apr 18, 2022 Single-Cell Analysis Yields Immune Cell Atlas of Aging, Uncovers Frailty-Specific Immune Monocyte Apr 14, 2022 Genomic Study of Mammalian Species Links Somatic Mutation Rate to Lifespan Mar 8, 2022 Multiomic Analyses Point to Organ-Specific Biological Aging Patterns Feb 18, 2022 InsideTracker Boosts Scientific Credentials for Genome-Driven Lifestyle Platform Premium Feb 17, 2022 Leukocyte Telomere Length Linked to Age, Sex, Ancestry in UK Biobank Analysis Dec 7, 2021 Pan-Cancer Analysis Reveals Unique Features in Tumors From Younger People Nov 11, 2021 Long-Lived Rockfish Genome Analysis Provides New Clues to Longevity Sep 30, 2021 Individuals With Polymerase Defects Have Increased Somatic Mutations, But Not Increased Aging Sep 22, 2021 Aviv Scientific Closes $40M Series B Financing Round Sep 14, 2021 Centenarian Exome Analysis Points to Conserved Longevity Pathways Jul 12, 2021 Aging Clock Developed From Inflammatory Immune Features Dec 2, 2020 2bPrecise Takes Precision Medicine Platform to Otolaryngology Practice as it Continues to Expand Premium Oct 14, 2020 Germline Variants Contribute to Risk of Developing Aging-Related Clonal Hematopoiesis Oct 1, 2020 Cancer Clues Gleaned from Somatic Mutation Patterns in Normal Bladders Jul 24, 2020 Norwegian Diagnostics Firm Age Labs to Develop Epigenetics-Based Test for SARS-CoV-2 Premium Jul 14, 2020 Deep Longevity Closes Series A, Partners With Human Longevity Jul 2, 2020 Translation of Dog Years Into Human Years Updated With Epigenetic Analysis Jun 19, 2020 Family Study Finds Germline Mutation Rates Predict Longevity, Fertility Apr 23, 2020 Elysium Health Licenses DNA Methylation Biomarkers From Yale University Load More Breaking News UBS Initiates Coverage of 10X Genomics, PacBio, Akoya Biosciences, NanoString Technologies Circadian Gene Expression Variation Across Tissue Types May Offer Aging, Disease Clues Siemens Healthineers Q1 Dx Revenues Fall 21 Percent; Firm Strikes Lab Analyzer Deal With Unilabs Becton Dickinson Fiscal Q1 Revenues Down 3 Percent; Firm Raises FY23 Guidance NanoString Technologies, Weill Cornell Medicine Collaborate on Spatial Atlas of Human Tissues The Scan White-Tailed Deer Harbor SARS-CoV-2 Variants No Longer Infecting Humans, Study Finds A new study in PNAS has found that white-tailed deer could act as a reservoir of SARS-CoV-2 variants no longer found among humans. Study Points to Benefits of Local Consolidative Therapy, Targeted Treatments in Cancer Care In JCO Precision Oncology, researchers report that local consolidative therapy combined with molecularly targeted treatments could improve survival for some lung cancer patients. Genetic Variants That Lower LDL Cholesterol Linked to Reduced Heart Disease Risk Rare variants in two genes that lower LDL cholesterol are also associated with a decreased risk of coronary heart disease, according to a new JAMA Cardiology study. Study Links Evolution of Longevity, Social Organization in Mammals With the help of comparative phylogenetics and transcriptomics, researchers in Nature Communications see ties between lifespan and social organization in mammals.