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aging

In Genome Research this week: links between biological aging and mutations affecting epigenetic regulators; long-read sequencing-based strategy to map chromatin accessibility; and more.

The long-running Framingham Heart Study has received a $38 million grant, according to the Boston Globe.

Some of the mutational signatures the researchers observed were similar to ones previously seen in B cell tumors, underscoring the link between aging and cancer.

Investigators found methylation models in conserved ribosomal DNA from mice also showed promise as age predictors in canine and human samples.

The company is developing a methylated DNA biomarker that will predict all-cause mortality risk and risk of developing certain age-related diseases.

Researchers uncover additional loci associated with lifespan, which the Telegraph says could be folded into a genetic test.

DNA sequence data from hundreds of individuals suggest that age, smoking, and alcohol use coincide with the expansion of clones containing NOTCH1 and PPM1D mutations.

In Genome Biology this week: catalog of curated human genes and transcripts; potential biomarkers for aging; and more.

Second X Helping

UCSF researchers find that having two X chromosomes may contribute to women's longer lifespans, according to Discover's D-brief blog.

Researchers have analyzed the genome of Lonesome George, the last Pinta tortoise, to find areas of selection affecting genes linked to aging and the immune system, Discover's D-brief blog says.

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Three genetic testing companies form a coalition to influence how Congress considers genetic privacy, The Hill reports.

University of California, San Diego researchers investigate how skin care products influence the skin microbiome, Scientific American reports.

The Wall Street Journal examines billing codes used by uBiome.

In PNAS this week: links between lung adenocarcinoma and lncRNA, algorithm to impute and cluster Hi-C interaction profiles from single cells, and more.