The buccal epithelial cell-based epigenetic clock corresponded with age in those under 20, but skewed slightly higher in a small subset of children with autism spectrum disorder.
From single-cell RNA sequence data on neurogenic brain samples from young and old mice, researchers saw T cell activity that seems to staunch neural stem cell proliferation.
In Genome Research this week: links between biological aging and mutations affecting epigenetic regulators; long-read sequencing-based strategy to map chromatin accessibility; and more.
Some of the mutational signatures the researchers observed were similar to ones previously seen in B cell tumors, underscoring the link between aging and cancer.
In Science this week: approach to measure microRNA targeting efficiency, strategy to conduct high-throughput chemical screens at single-cell resolution, and more.
