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aging

Researchers identified one germline variant near TET2 that appears to be specific to individuals of African ancestry.

In Science this week: somatic mutation heterogeneity among human bladder samples, and more.

With targeted, exome, and whole-genome sequencing data, investigators saw recurrent driver mutations and heterogeneous mutational signatures in seemingly normal bladders.

The Oslo-based company plans to develop a test that can identify high-risk individuals based on an epigenetic signature.

Spun out of Insilico Medicine in January, Deep Longevity is developing artificial intelligence-based systems to track aging based on various biomarkers.

Dogs age more rapidly in their early years but then age more slowly later on, a DNA methylome analysis found, changing how dogs' ages are translated to human ages.

Study subjects of both sexes who had low germline mutation rates lived nearly five years longer than individuals with high mutation rates.

In Genome Research this week: target-mismatched sgRNA in microbial genome editing, strategy to examine gene expression throughout the cell cycle, and more.

Lifespan Effects

Science reports that very rare genetic mutations in combination may take years off people's lives.

The company markets anti-aging supplements and a direct-to-consumer DNA methylation analysis kit designed to provide information about biological age.

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The head of Operation Warp Speed tells Bloomberg he expects the paused AstraZeneca and Johnson & Johnson vaccine trials to resume soon.

A new UK government says socioeconomic factors, not genetics, account for disparities in deaths due to COVID-19 between ethnic groups, the Financial Times reports.

NPR reports on an Alzheimer's disease drug trial that is continuing despite the pandemic.

In Nature this week: CRISPR-Cas3 system for making large deletions efficiently, more.