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Clonal Hematopoiesis Linked to Common, Rare Genetic Variants

Analyzing almost 628,400 exome sequences, researchers found common and rare variants corresponding with different forms of clonal hematopoiesis of indeterminate potential.

Regulatory Alterations Overrepresented in Single-Cell Sequence Data From Individual Neurons

Researchers profile somatic mutation patterns in individual neurons from the prefrontal cortex using new and published single-cell sequences spanning 17 individuals.

Age Labs, BioAge to Mine Norwegian Biobank Cohort to Produce New Diagnostics, Drugs
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The partnership will see the two companies scour a Norwegian biobank for data that could produce a multitude of new aging-related tests, therapies, and perhaps companion diagnostics.

Heart Dysfunction Insights Drawn From Age-Related Cardiomyocyte Mutations

Researchers used single-cell whole-genome sequencing to track somatic point mutations in heart cardiomyocytes in samples from infants to elderly individuals.

Imagene Labs, Kalbe Partner for Genetic Risk Tests

Kalbe is launching two new tests that employ ancestry-based genetic risk scoring technology developed by Imagene Labs in Singapore.

Apr 20, 2022

Advanced Alzheimer's Disease Linked to Somatic Mutation Rise in Neuronal Cells

Apr 18, 2022

Single-Cell Analysis Yields Immune Cell Atlas of Aging, Uncovers Frailty-Specific Immune Monocyte

Apr 14, 2022

Genomic Study of Mammalian Species Links Somatic Mutation Rate to Lifespan

Mar 8, 2022

Multiomic Analyses Point to Organ-Specific Biological Aging Patterns

Feb 18, 2022

InsideTracker Boosts Scientific Credentials for Genome-Driven Lifestyle Platform
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Feb 17, 2022

Leukocyte Telomere Length Linked to Age, Sex, Ancestry in UK Biobank Analysis

Dec 7, 2021

Pan-Cancer Analysis Reveals Unique Features in Tumors From Younger People

Nov 11, 2021

Long-Lived Rockfish Genome Analysis Provides New Clues to Longevity

Sep 30, 2021

Individuals With Polymerase Defects Have Increased Somatic Mutations, But Not Increased Aging

Sep 22, 2021

Aviv Scientific Closes $40M Series B Financing Round

Sep 14, 2021

Centenarian Exome Analysis Points to Conserved Longevity Pathways

Jul 12, 2021

Aging Clock Developed From Inflammatory Immune Features

Dec 2, 2020

2bPrecise Takes Precision Medicine Platform to Otolaryngology Practice as it Continues to Expand
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Oct 14, 2020

Germline Variants Contribute to Risk of Developing Aging-Related Clonal Hematopoiesis

Oct 1, 2020

Cancer Clues Gleaned from Somatic Mutation Patterns in Normal Bladders

Jul 24, 2020

Norwegian Diagnostics Firm Age Labs to Develop Epigenetics-Based Test for SARS-CoV-2
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Jul 14, 2020

Deep Longevity Closes Series A, Partners With Human Longevity

Jul 2, 2020

Translation of Dog Years Into Human Years Updated With Epigenetic Analysis

Jun 19, 2020

Family Study Finds Germline Mutation Rates Predict Longevity, Fertility

Apr 23, 2020

Elysium Health Licenses DNA Methylation Biomarkers From Yale University

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The Scan

White-Tailed Deer Harbor SARS-CoV-2 Variants No Longer Infecting Humans, Study Finds

A new study in PNAS has found that white-tailed deer could act as a reservoir of SARS-CoV-2 variants no longer found among humans.

Study Points to Benefits of Local Consolidative Therapy, Targeted Treatments in Cancer Care

In JCO Precision Oncology, researchers report that local consolidative therapy combined with molecularly targeted treatments could improve survival for some lung cancer patients.

Genetic Variants That Lower LDL Cholesterol Linked to Reduced Heart Disease Risk

Rare variants in two genes that lower LDL cholesterol are also associated with a decreased risk of coronary heart disease, according to a new JAMA Cardiology study.

Study Links Evolution of Longevity, Social Organization in Mammals

With the help of comparative phylogenetics and transcriptomics, researchers in Nature Communications see ties between lifespan and social organization in mammals.