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aging

The long-running Framingham Heart Study has received a $38 million grant, according to the Boston Globe.

Some of the mutational signatures the researchers observed were similar to ones previously seen in B cell tumors, underscoring the link between aging and cancer.

Investigators found methylation models in conserved ribosomal DNA from mice also showed promise as age predictors in canine and human samples.

The company is developing a methylated DNA biomarker that will predict all-cause mortality risk and risk of developing certain age-related diseases.

For Long Life

Researchers uncover additional loci associated with lifespan, which the Telegraph says could be folded into a genetic test.

DNA sequence data from hundreds of individuals suggest that age, smoking, and alcohol use coincide with the expansion of clones containing NOTCH1 and PPM1D mutations.

In Genome Biology this week: catalog of curated human genes and transcripts; potential biomarkers for aging; and more.

Second X Helping

UCSF researchers find that having two X chromosomes may contribute to women's longer lifespans, according to Discover's D-brief blog.

Researchers have analyzed the genome of Lonesome George, the last Pinta tortoise, to find areas of selection affecting genes linked to aging and the immune system, Discover's D-brief blog says.

An Australian team has sequenced some 4,000 healthy individuals over 70 years old for the Medical Genome Reference Bank database.

Pages

Bloomberg reports that the DNA-for-cash deal reported in Kentucky might be a more widespread scam.

St. Jude Children's Research Hospital scientists have treated infants with X-linked severe combined immunodeficiency using gene therapy in an early phase study.

St. Louis Public Radio reports that some African Americans are turning to DNA ancestry testing to help guide genealogical searches.

In Nature this week: a genomic analysis of the snailfish Pseudoliparis swirei, ancient DNA analysis gives insight into the introduction of farming to England, and more.