aging

For Long Life

Researchers uncover additional loci associated with lifespan, which the Telegraph says could be folded into a genetic test.

DNA sequence data from hundreds of individuals suggest that age, smoking, and alcohol use coincide with the expansion of clones containing NOTCH1 and PPM1D mutations.

In Genome Biology this week: catalog of curated human genes and transcripts; potential biomarkers for aging; and more.

Second X Helping

UCSF researchers find that having two X chromosomes may contribute to women's longer lifespans, according to Discover's D-brief blog.

Researchers have analyzed the genome of Lonesome George, the last Pinta tortoise, to find areas of selection affecting genes linked to aging and the immune system, Discover's D-brief blog says.

An Australian team has sequenced some 4,000 healthy individuals over 70 years old for the Medical Genome Reference Bank database.

Researchers saw frequent somatic mutations in esophageal tissue from nine individuals, including mutations under positive selection in 14 oncogenes.

This Week in PNAS

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.

And That's It

Business Insider reports that a three-year partnership between Ancestry and Calico has ended.

The researchers were able to diagnose 17 patients with short telomere syndrome based on telomere length combined with targeted sequence data.

Pages

Reuters reports that UK researchers are using gene-editing tools to develop flu-resistant chickens.

Nature calls for genomics to become part of the World Health Organization's cholera surveillance approach.

Vox explores a proposal to institute a lottery system to award grant funds.

In Genome Biology this week: gut microbiome study of individuals from Tanzania and Botswana, sixth version of the Network of Cancer Genes database, and more.