aging

Using a mass cytometry method called EpiTOF, researchers profiled histone modifications and variants in a range of immune cell types across individuals of different ages.

Chromatin immunoprecipitation sequencing showed divergent H4K16ac histone acetylation patterns in brain samples from young, old, and AD-affected individuals.

Long Lives of Bats

Researchers report that the telomeres of a long-lived bat don't shorten with age.

This Week in Nature

In Nature this week: nanopore sequencing and assembly human genome, method to reduce CRISPR off-target effects, and more.

As organisms age, their transcriptomic signatures shift from looking more like those observed in cancer to those seen in degenerative chronic diseases.

Research teams documented mosaic mutations during brain development, as well as rising somatic mutations in aging brains or brains affected by neurodegenerative disease.

A null mutation in the SERPINE1 gene was associated with longer telomeres and increased longevity among carriers, a new study found.

For Long Life

A new sample of supercentenarian genomes is to be available to researchers this week, the New York Times reports.

Bioage Labs now intends to set up an internal laboratory to experiment with different compounds, while building out its team.

With discovery and replication meta-analyses on data for more than 100,000 individuals, researchers identified variants that influence lean mass near five genes.

Pages

Lawmakers have asked four direct-to-consumer genetic testing companies to explain their privacy policies and security measures, according to Stat News.

The Trump Administration has proposed a plan to reorganize the federal government, the Washington Post reports.

In Science this week: genetic overlap among many psychiatric disorders, and more.

The Economist writes that an increasing number of scientific journals don't do peer review.