aging

A comparison of unstimulated and stimulated CD4+ T cells from young and old mice in two subspecies showed rising cell-to-cell expression variability with age.

Columbia University researchers uncover a gene variant associated with differential aging in the brain after the age of 65.

The study will involve assaying proteomic markers for dementias including Alzheimer's disease, and understanding genomic markers as part of the normal aging process.

This Week in Science

In Science this week: imaging approach to visual epigenetic activity in the brain, and more.

The companies will collaborate to identify personalized aging-related biomarkers based on individuals' age-annotated genomic and transcriptomic data.

In Genome Biology this week: methylation changes in aging, single-cell RNA sequencing of renal cell carcinoma tumor, and more.

Craig Venter's Human Longevity is deeply phenotyping individuals and capturing their genetic profiles to explore aging.

This Week in Cell

In Cell this week: transcriptional map of human embryo development, circadian clock genes in acute myeloid leukemia, and more.

Low-frequency mutations in the TP53 gene were reported in peritoneal fluid from women with or without ovarian cancer, but more so in women with the disease.

Compound variants in MC1R are linked to perceived facial age, according to a genome-wide association involving thousands of elderly Europeans.

Pages

Dog DNA testing finds that some purebreds might not truly be purebreds, Inside Edition reports.

Mary Beckerle has returned as director of the Huntsman Cancer Institute, according to ScienceInsider.

Smithsonian Magazine reports that environmental DNA sampling can be used to track elusive organisms.

In Genome Research this week: repetitive satellite DNA in the fruit fly, transcriptome map assembly pipeline, and more.