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aging

In Genome Research this week: target-mismatched sgRNA in microbial genome editing, strategy to examine gene expression throughout the cell cycle, and more.

Lifespan Effects

Science reports that very rare genetic mutations in combination may take years off people's lives.

The company markets anti-aging supplements and a direct-to-consumer DNA methylation analysis kit designed to provide information about biological age.

In PNAS this week: analysis of 1,200 high-coverage Samoan genome sequences, metabolites associated with frailty among the elderly, and more.

Young at Brain

Certain gene variants in conjunction with a healthy lifestyle may keep brains young, according to New Scientist.

In Nature this week: epigenetic factors that prevent healthy aging and more.

Researchers analyzed the gut microbiome makeup of more than 600 older individuals before and after adhering to their usual diet or a Mediterranean diet for a year.

In PNAS this week: remethylation of DNMT3A in mice affects expansion of myeloid cells, glycan and receptor expression in glioblastoma, and more.

Transcriptome profiles in ovarian cells from young and old non-human primates unearthed expression changes that coincided with flagging fertility in humans.

The Medical Genome Reference Bank, which currently holds data for more than 2,500 healthy elderly Australians, could help scientists understand the genetics of healthy aging.

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Nobel laureates and scientific societies urge NIH and the Department of Health and Human Services to revisit the recent decision to end funding for a coronavirus grant.

Bloomberg reports that BGI's SARS-CoV-2 testing sites in the Middle East have raised concerns among US officials.

A new Pew Research Center poll finds confidence in medical researchers has grown among US adults since the start of the coronavirus pandemic.

In Science this week: machine learning algorithm for faster Mendelian disorder diagnoses, gene linked to safe response to nitrogen-containing bisphosphonates, and more.