adverse events
Physicians are intrigued by the concept but want to see more data on the benefits of medical cannabis and on the underlying genetic links that can facilitate personalization.
While four genetic mutations have been associated with the risk of developing PML, there is not consensus on which drugs merit preventive screening.
The three-year Ubiquitous Pharmacogenomics Consortium's PREPARE study enrolled nearly 7,000 patients in seven European countries.
FDA Updates Xeloda Labeling to Make DPYD Variant Risks More Explicit
In response to a citizen petition, the FDA has added more specific language about testing patients for DPYD gene variants that place them at risk for severe treatment-related toxicities.
New IBD Adverse Drug Response Risk Gene Identified
Genome- and exome-wide association analysis on inflammatory bowel disease patients with or without thiopurine-induced myelosuppression revealed new and known risk genes.