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Researchers uncovered ties between a germline VSIG10L mutation, inherited forms of Barrett esophagus, and related esophageal cancer cases.

NEW YORK (GenomeWeb) — Members of the Lung Cancer Mutation Consortium have reported that patients who received targeted therapy based on their molecular testing results had significantly improved survival compared to those who did not, in study of more than 1,000 lung cancers tested by the consor

NEW YORK (GenomeWeb) — Members of the Lung Cancer Mutation Consortium have reported data from more than 1,000 lung cancer patients tested for cancer driver mutations over a period of four years, finding a significant improvement in median survival among patients who received targeted therapy base

Originally published Oct. 8

A team led by clinical researchers from the University of North Carolina, Chapel Hill, has published a peer-reviewed study describing the development and validation of a gene expression-based predictor of lung cancer histology for formalin-fixed, paraffin-embedded tissue samples.

The American Society of Clinical Oncology held its annual meeting June 1 - 5 in Chicago. The following are abstracts presented at the meeting focused on the application of molecular diagnostics to cancer prognosis.

Transcriptome sequencing is quickly gaining ground for disease studies due to its ability to provide information on gene expression and alternative splicing events — information not available from exome sequencing or whole-genome sequencing studies.

Clarient plans to commercialize Applied Genomics' five-antibody immunohistochemistry test for non-small cell lung cancer, called Pulmotype, within its network of pathologists by the first quarter of 2010.

Launch Pad for Rising Stars


Rick Wilson, a bushwhacker involved in the sequencing for the Human Genome Project, is mentoring a new generation of trailblazers in 21st century genomics.

Genomics vs. Cancer


Recent advances in the battle against cancer have come from sequencing, microRNAs, barcode arrays, disease stratification, pathway analysis, and more.

In Science this week: convergent evolution in bird hemoglobin, and more.

The Wall Street Journal speaks with patients affected by questionable test results from Theranos.

Researchers link variants in TACR3 to hot flashes during menopause, Live Science reports.

Kuwait says it will alter its law requiring citizens and visitors to provide DNA samples, New Scientist reports.