adenocarcinoma

A new analysis hints that adenocarcinomas or squamous cell carcinomas may have certain overlapping expression patterns, regardless of the tissue of origin.

An international research team profiled more than 7,500 tumor genomes, including small-bowel adenocarcinoma, colorectal cancer, and gastric cancer genomes.

Researchers uncovered ties between a germline VSIG10L mutation, inherited forms of Barrett esophagus, and related esophageal cancer cases.

NEW YORK (GenomeWeb) — Members of the Lung Cancer Mutation Consortium have reported that patients who received targeted therapy based on their molecular testing results had significantly improved survival compared to those who did not, in study of more than 1,000 lung cancers tested by the consor

NEW YORK (GenomeWeb) — Members of the Lung Cancer Mutation Consortium have reported data from more than 1,000 lung cancer patients tested for cancer driver mutations over a period of four years, finding a significant improvement in median survival among patients who received targeted therapy base

Originally published Oct. 8

A team led by clinical researchers from the University of North Carolina, Chapel Hill, has published a peer-reviewed study describing the development and validation of a gene expression-based predictor of lung cancer histology for formalin-fixed, paraffin-embedded tissue samples.

The American Society of Clinical Oncology held its annual meeting June 1 - 5 in Chicago. The following are abstracts presented at the meeting focused on the application of molecular diagnostics to cancer prognosis.

Transcriptome sequencing is quickly gaining ground for disease studies due to its ability to provide information on gene expression and alternative splicing events — information not available from exome sequencing or whole-genome sequencing studies.

Clarient plans to commercialize Applied Genomics' five-antibody immunohistochemistry test for non-small cell lung cancer, called Pulmotype, within its network of pathologists by the first quarter of 2010.

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Researchers find that a personalized medicine approach could help people who experience pain while taking statins, New Scientist reports.

US National Science Foundation is continuing its responsible research conduct training policy despite its flaws, ScienceInsider reports.

A CRISPR-themed meeting explored how the tool could and should be used, Wired reports.

In Science this week: database of proteins' effects on cancer, targeted error correction sequencing, and more.