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adenocarcinoma

Researchers uncovered ties between a germline VSIG10L mutation, inherited forms of Barrett esophagus, and related esophageal cancer cases.

NEW YORK (GenomeWeb) — Members of the Lung Cancer Mutation Consortium have reported that patients who received targeted therapy based on their molecular testing results had significantly improved survival compared to those who did not, in study of more than 1,000 lung cancers tested by the consor

NEW YORK (GenomeWeb) — Members of the Lung Cancer Mutation Consortium have reported data from more than 1,000 lung cancer patients tested for cancer driver mutations over a period of four years, finding a significant improvement in median survival among patients who received targeted therapy base

Originally published Oct. 8

A team led by clinical researchers from the University of North Carolina, Chapel Hill, has published a peer-reviewed study describing the development and validation of a gene expression-based predictor of lung cancer histology for formalin-fixed, paraffin-embedded tissue samples.

The American Society of Clinical Oncology held its annual meeting June 1 - 5 in Chicago. The following are abstracts presented at the meeting focused on the application of molecular diagnostics to cancer prognosis.

Transcriptome sequencing is quickly gaining ground for disease studies due to its ability to provide information on gene expression and alternative splicing events — information not available from exome sequencing or whole-genome sequencing studies.

Clarient plans to commercialize Applied Genomics' five-antibody immunohistochemistry test for non-small cell lung cancer, called Pulmotype, within its network of pathologists by the first quarter of 2010.

Launch Pad for Rising Stars

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Rick Wilson, a bushwhacker involved in the sequencing for the Human Genome Project, is mentoring a new generation of trailblazers in 21st century genomics.

Genomics vs. Cancer

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Recent advances in the battle against cancer have come from sequencing, microRNAs, barcode arrays, disease stratification, pathway analysis, and more.

Harold Varmus, a former NIH director, says that proposed reductions to the agency's budget are worrisome.

The Genome 10K project is to sequence about 10,000 vertebrate genomes, including ones of endangered species, Digital Trends reports.

The new Coalition to Save NIH Funding aims to educate lawmakers and the public on the significance of biomedical research.

In PLOS this week: analysis of viral sequences from human blood samples, gut microbiomes of heart failure patients, and more.