Skip to main content
Premium Trial:

Request an Annual Quote

Response Genetics Licenses BRAF Mutation Technology to GlaxoSmithKline

By a GenomeWeb staff reporter

NEW YORK (GenomeWeb News) – Response Genetics today said that it has licensed to GlaxoSmithKline non-exclusive rights to its PCR technology and "diagnostic expertise" to assess BRAF gene mutations in human tumor samples.

The BRAF gene encodes B-Raf proto-oncogene serine/threonine-protein kinase, a protein that is involved in cell signaling and cellular growth and differentiation. Mutations of the gene have been associated with the development of certain forms of cancer, particularly melanoma, and GSK is one of multiple drug firms pursuing the development of BRAF inhibitors.

Los Angeles-based Response Genetics said that it will receive certain agreed-to milestone payments, but further financial terms of the agreement were not disclosed.

Kathleen Danenberg, president and CEO of Response Genetics, noted that the firm already provides GSK with genetic testing services to support its drug development programs.

Response Genetics sells its ResponseDX: Colon, ResponseDX: Lung, and ResponseDX: Gastric genetic test panels in the US directly and through an agreement with NeoGenomics Laboratories inked in September 2008. All of the tests are performed at Response Genetics' CLIA-certified lab.

In Tuesday afternoon trade on the Nasdaq, shares of Response Genetics were up 32 percent at $2.83.

The Scan

Two J&J Doses

Johnson & Johnson says two doses of its SARS-CoV-2 vaccine provides increased protection against symptomatic COVID-19, CNN reports.

Pfizer-BioNTech Vaccine Response in Kids

The Pfizer-BioNTech SARS-CoV-2 vaccine in a lower-dose format appears to generate an immune response among children, according to the Washington Post.

Chicken Changes to Prevent Disease

The Guardian writes that researchers are looking at gene editing chickens to help prevent future pandemics.

PNAS Papers on Siberian Dog Ancestry, Insect Reproduction, Hippocampal Neurogenesis

In PNAS this week: ancestry and admixture among Siberian dogs, hormone role in fruit fly reproduction, and more.